Intra-articular injections for the treatment of osteoarthritis: Focus on the clinical use of hyaluronic acid

被引：79
作者：
Iannitti T. [1 ]
Lodi D. [2 ]
Palmieri B. [3 ]
机构：
[1] Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow
[2] Department of Nephrology, Dialysis and Transplantation, University of Modena, Reggio Emilia Medical School, Modena
[3] Department of General Surgery and Surgical Specialties, Reggio Emilia Medical School, University of Modena, Modena
来源：
Drugs in R & D | 2011年 / 11卷 / 1期
关键词：
Hyaluronic-acid; Osteoarthritis; Rheumatoid-arthritis; therapeutic use; treatment;
D O I：
10.2165/11539760-000000000-00000
中图分类号：
学科分类号：
摘要：
Osteoarthritis (OA), also called degenerative joint disease, is the most frequently occurring chronic musculoskeletal disease, particularly affecting the aging population. The use of viscosupplementation, i.e. intra-articular (IA) hyaluronic acid (HA) drug therapy, to treat OA, is growing worldwide, due to important results obtained from several clinical trials, which reported IA HA-related improvements in functional activity and pain management. This review is an update of the IA use of this compound in the treatment of OA, with clinical evidence from the last few years being discussed and used to delineate new trends for the future. © 2011 Iannitti et al., publisher and licensee Adis Data Information BV.
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页码：13 / 27
页数：14
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