Synthesis of substituted benzofurans by condensation of arylglyoxals with enols and phenols

被引:0
|
作者
Yu. О. Gorbunov
А. N. Komogortsev
V. S. Mityanov
B. V. Lichitskii
A. A. Dudinov
K. A. Lyssenko
М. М. Krayushkin
机构
[1] Russian Academy of Sciences,N. D. Zelinsky Institute of Organic Chemistry
[2] D. I. Mendeleev University of Chemical Technology of Russia,A. N. Nesmeyanov Institute of Organoelement Compounds
[3] Russian Academy of Sciences,undefined
来源
Russian Chemical Bulletin | 2018年 / 67卷
关键词
multicomponent condensation; arylglyoxals; heterocyclization; enols; pyrid inium salts; 4-dimethylaminopyridine; 4-hydroxy-6-methyl-2; -pyran-2-one; 5,5-dimethylcyclohexane- 1,3-dione; 2-hydroxynaphthalene-1,4-dione; 2-naphthol; 3,4-methylenedioxyphenol; benzofurans;
D O I
暂无
中图分类号
学科分类号
摘要
A convenient method for the synthesis of previously unknown substituted 3-hydroxy-5,5- dimethyl-2-(2-arylbenzofuran-3-yl)cyclohex-2-enones, 4-hydroxy-6-methyl-3-(2-arylbenzofuran- 3-yl)-2H-pyran-2-ones, and 2-hydroxy-3-(2-arylbenzofuran-3-yl) naphthoquinones was developed based on the reaction of 3,4-methylenedioxyphenol or 2-naphthol with pyridinium salts obtained by multicomponent condensation of arylglyoxals with carbo- or heterocyclic enols and 4-dimethylaminopyridine.
引用
收藏
页码:504 / 509
页数:5
相关论文
共 50 条
  • [1] Synthesis of substituted benzofurans by condensation of arylglyoxals with enols and phenols
    Gorbunov, Yu. O.
    Komogortsev, A. N.
    Mityanov, V. S.
    Lichitskii, B. V.
    Dudinov, A. A.
    Lyssenko, K. A.
    Krayushkin, M. M.
    RUSSIAN CHEMICAL BULLETIN, 2018, 67 (03) : 504 - 509
  • [2] Synthesis of condensed furylacetic acids based on multicomponent condensation of heterocyclic enols with arylglyoxals and Meldrum's acid
    Gorbunov, Yurii O.
    Lichitsky, Boris V.
    Komogortsev, Andrei N.
    Mityanov, Vitaly S.
    Dudinov, Arkadii O.
    Krayushkin, Mikhail M.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2018, 54 (07) : 692 - 695
  • [3] Synthesis of Condensed Furylacetic Acids Based on Multicomponent Condensation of Heterocyclic Enols with Arylglyoxals and Meldrum's Acid
    Yurii О. Gorbunov
    Boris V. Lichitsky
    Andrei N. Komogortsev
    Vitaly S. Mityanov
    Arkadii А. Dudinov
    Mikhail M. Krayushkin
    Chemistry of Heterocyclic Compounds, 2018, 54 : 692 - 695
  • [4] Synthesis of multi-functionalized benzofurans through the condensation of ninhydrin and phenols using SSA as a recyclable heterogeneous acid catalyst
    Ashis Kundu
    Animesh Pramanik
    Molecular Diversity, 2016, 20 : 619 - 626
  • [5] Synthesis of multi-functionalized benzofurans through the condensation of ninhydrin and phenols using SSA as a recyclable heterogeneous acid catalyst
    Kundu, Ashis
    Pramanik, Animesh
    MOLECULAR DIVERSITY, 2016, 20 (03) : 619 - 626
  • [6] Three-component synthesis of tetrasubstituted pyrroles by condensation with amines and arylglyoxals
    Nadezhda N. Kolos
    Viktoriya V. Zubar
    Irina V. Omelchenko
    Vladimir I. Musatov
    Chemistry of Heterocyclic Compounds, 2016, 52 : 237 - 243
  • [7] Three-component condensation of 1,3-dimethyl-barbituric acid, arylglyoxals, and substituted thioureas
    N. N. Kolos
    L. L. Zamigailo
    N. V. Chechina
    I. V. Omel’chenko
    O. V. Shishkin
    E. V. Vashchenko
    Chemistry of Heterocyclic Compounds, 2013, 48 : 1817 - 1823
  • [8] Three-component condensation of 1,3-dimethyl-barbituric acid, arylglyoxals, and substituted thioureas
    Kolos, N. N.
    Zamigailo, L. L.
    Chechina, N. V.
    Omel'chenko, I. V.
    Shishkin, O. V.
    Vashchenko, E. V.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2013, 48 (12) : 1817 - 1823
  • [9] Some Recent Approaches to the Synthesis of 2-Substituted Benzofurans
    De Luca, Lidia
    Nieddu, Giammario
    Porcheddu, Andrea
    Giacomelli, Giampaolo
    CURRENT MEDICINAL CHEMISTRY, 2009, 16 (01) : 1 - 20
  • [10] Ga(OTf)3-mediated synthesis of substituted benzofurans
    Wang, Heui-Sin
    Chan, Chieh-Kai
    Chang, Meng-Yang
    TETRAHEDRON, 2016, 72 (33) : 5132 - 5141