Nora's lesion. Discussion of a rare bone proliferation

被引:6
作者
Adler, D. [1 ]
Aigner, T. [2 ]
von Salis-Soglio, G. [1 ]
Gutberlet, M. [3 ]
Heyde, C. -E. [1 ]
机构
[1] Univ Leipzig, Orthopad Klin & Poliklin, D-04103 Leipzig, Germany
[2] Univ Leipzig, Inst Pathol, D-04103 Leipzig, Germany
[3] Univ Leipzig, Abt Diagnost & Intervent Radiol, Herzzentrum, D-04103 Leipzig, Germany
来源
ORTHOPADE | 2010年 / 39卷 / 11期
关键词
Proliferation; Cancer of bone; Radiology; Histology; PAROSTEAL OSTEOCHONDROMATOUS PROLIFERATION; TRANSLOCATION;
D O I
10.1007/s00132-010-1648-7
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Nora's lesion, also known as "bizarre parosteal osteochondromatous proliferation" (BPOP), was first described in 1983 by the pathologist Nora. This lesion is defined as a proliferation of the bone. In most cases the lesion emanates from the intact cortical substance of short bones. It used to be assigned to reactive, heterotopic ossifications. More recent publications described constant genetic alterations supposing a tumorous genesis. Nora lesions are mostly found in the third or fourth decade of life; a preference of sexes is not described in the literature, They are characterized by a typical appearance in radiological diagnostics, but the diagnosis is ultimately determined by histopathological examination. Surgical resection is the therapy of choice. We report the case of a 29-year-old patient with an undetermined proliferation of the proximal ulna. The diagnosis of a Nora's lesion was made. The therapeutic approach, differential diagnosis and corresponding literature are presented and discussed.
引用
收藏
页码:1065 / 1070
页数:6
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