Helicobacter pylori in patients with gastritis in West Cameroon: Prevalence and risk factors for infection

被引：11

作者：

Agbor N.E. ^{[1
]}

Esemu S.N. ^{[1
,2
]}

Ndip L.M. ^{[1
,2
]}

Tanih N.F. ^{[3
]}

Smith S.I. ^{[4
]}

Ndip R.N. ^{[1
,2
]}

机构：

[1] Department of Microbiology and Parasitology, University of Buea, P. O. Box 63, Buea

[2] Laboratory for Emerging Infectious Diseases, University of Buea, Buea

[3] Medical Research Council Unit, Fajara

[4] Nigerian Institute of Medical Research, Lagos

来源：

BMC Research Notes | / 11卷 / 1期

关键词：

Cameroon; Gastritis; Helicobacter pylori; Prevalence; Risk factors;

D O I：

10.1186/s13104-018-3662-5

中图分类号：

学科分类号：

摘要：

Objectives: Helicobacter pylori is a pathogenic bacterium that parasitizes the gastric mucous layer and the epithelial lining of the stomach causing duodenal ulcers, gastric ulcers and cardiovascular disease amongst others. This study aimed at establishing the epidemiologic profile of H. pylori infection in gastritis patients presenting at the Melong District Hospital. Results: Blood, stool and epidemiological data collected from 500 patients were analyzed for the presence of H. pylori antibody in serum, antigen in stool and elucidation of risk factors captured in questionnaires. Of 500 blood samples, 217 (43.4%) were seropositive with male and female seroprevalences of 45.5% (61/134) and 42.6% (156/366) respectively. Similarly, 47.4% (237/500) samples tested positive for stool antigen with prevalences of 47.0% (63/134) for males and 47.5% (174/366) for females. The antigen prevalence was higher (53.2%; 118/222) in older patients (> 50 years) than in younger patients (42.8%; 119/278; P = 0.021). The antigen test had a higher (47.4%) prevalence than the antibody test (43.4%). Educational level, source of income, source of drinking water, age of patients, and alcohol consumption had positive associations with H. pylori infection. These results have clinical and epidemiological significance and call for intervention to mitigate the situation. © 2018 The Author(s).

引用

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