Precise Functionalization of Remote C-H Bonds

被引：0
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作者：
Zeshui Liu
Honggang Cheng
Qianghui Zhou
机构：
[1] Wuhan University,College of Chemistry and Molecular Sciences
来源：
Chemical Research in Chinese Universities | 2020年 / 36卷
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摘要：
Remote C-H bond functionalization of arenes with precise control is a recognized extraordinary challenge in organic synthesis. Recently, Yu and Houk et al. developed an elegant strategy to distinguish and functionalize remote Csp2-H bonds of (hetero)arenes within one-bond distance by the interplay of a remote directing template and a transient norbornene-type mediator. A wide range of medicinally important benzoazines are well compatible with this method. The chemistry significantly expands the toolbox for site-selective functionalization of remote Csp2-H bond of (hetero)arenes. This work has been published in Nature Chemistry in March, 2020.
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页码：727 / 728
页数：1
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