Protamine Sulfate Enhances the Transduction Efficiency of Recombinant Adeno-Associated Virus-Mediated Gene Delivery

被引:0
作者
Ya-Wun Yang
Yuan-Chiao Hsieh
机构
[1] National Taiwan University,School of Pharmacy, College of Medicine
来源
Pharmaceutical Research | 2001年 / 18卷
关键词
recombinant adeno-associated virus; protamine sulfate; gene delivery; hepatoma cells; zeta potential;
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学科分类号
摘要
Purpose. The purpose of this study was to evaluate glucose responsiveness in HepG2 human hepatoma cells transduced by a recombinant adeno-associated virus (rAAV) vector containing the insulin gene promoter, and to investigate the effect of protamine sulfate on rAAV-mediated gene delivery.
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页码:922 / 927
页数:5
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