Reference-based phasing using the Haplotype Reference Consortium panel

被引：0
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作者：
Po-Ru Loh
Petr Danecek
Pier Francesco Palamara
Christian Fuchsberger
Yakir A Reshef
Hilary K Finucane
Sebastian Schoenherr
Lukas Forer
Shane McCarthy
Goncalo R Abecasis
Richard Durbin
Alkes L Price
机构：
[1] Harvard T.H. Chan School of Public Health,Department of Epidemiology
[2] Program in Medical and Population Genetics,Department of Biostatistics
[3] Broad Institute of Harvard and MIT,Department of Computer Science
[4] Wellcome Trust Sanger Institute,Department of Mathematics
[5] Wellcome Trust Genome Campus,Division of Genetic Epidemiology, Department of Medical Genetics
[6] Center for Biomedicine,Department of Biostatistics
[7] European Academy of Bozen/Bolzano (EURAC),undefined
[8] affiliated with the University of Lübeck,undefined
[9] Center for Statistical Genetics,undefined
[10] University of Michigan,undefined
[11] Harvard University,undefined
[12] Massachusetts Institute of Technology,undefined
[13] Molecular and Clinical Pharmacology,undefined
[14] Medical University of Innsbruck,undefined
[15] Harvard T.H. Chan School of Public Health,undefined
来源：
Nature Genetics | 2016年 / 48卷
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摘要：
Po-Ru Loh, Alkes Price and colleagues present Eagle2, a reference-based phasing algorithm that allows for highly accurate and efficient phasing of genotypes across a broad range of cohort sizes. They demonstrate an approximately 10% improvement in accuracy and 20% improvement in speed compared to a competing method, SHAPEIT2.
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页码：1443 / 1448
页数：5
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