Research progress of post-acute sequelae after SARS-CoV-2 infection

被引：15
作者：
Jiao, Taiwei [1 ]
Huang, Yuling [2 ]
Sun, Haiyan [3 ]
Yang, Lina [2 ,4 ]
机构：
[1] China Med Univ, Dept Gastroenterol & Endoscopy, Hosp 1, Shenyang 110001, Liaoning, Peoples R China
[2] China Med Univ, Dept Geriatr, Hosp 1, Shenyang 110001, Liaoning, Peoples R China
[3] China Med Univ, Sch Stomatol, Dept Endodont, Shenyang 110001, Liaoning, Peoples R China
[4] China Med Univ, Hosp 1, Dept Int Phys Examinat Ctr, Shenyang 110001, Liaoning, Peoples R China
来源：
CELL DEATH & DISEASE | 2024年 / 15卷 / 04期
基金：
中国国家自然科学基金;
关键词：
HOSPITALIZED-PATIENTS; AFTER-DISCHARGE; COVID-19; PATIENTS; CYTOKINE STORM; SURVIVORS; DYSFUNCTION; MANIFESTATIONS; PREVALENCE; MANAGEMENT; RECOVERY;
D O I：
10.1038/s41419-024-06642-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
SARS-CoV-2 has spread rapidly worldwide and infected hundreds of millions of people worldwide. With the increasing number of COVID-19 patients discharged from hospitals, the emergence of its associated complications, sequelae, has become a new global health crisis secondary to acute infection. For the time being, such complications and sequelae are collectively called "Post-acute sequelae after SARS-CoV-2 infection (PASC)", also referred to as "long COVID" syndrome. Similar to the acute infection period of COVID-19, there is also heterogeneity in PASC. This article reviews the various long-term complications and sequelae observed in multiple organ systems caused by COVID-19, pathophysiological mechanisms, diagnosis, and treatment of PASC, aiming to raise awareness of PASC and optimize management strategies.
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页数：16
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