Haplotype structure of MSTN, IGF1, and BMP2 genes in Tunisian goats (Capra hircus) and their association with morphometric traits

被引：0
作者：
Sarra Chalbi
Maria Luisa Dettori
M’Naouer Djemali
Giuseppe Massimo Vacca
Elena Petretto
Michele Pazzola
Sonia Bedhiaf-Romdhani
机构：
[1] National Agronomic Institute of Tunisia,Laboratoire Des Productions Animales Et Fourragères
[2] Institut National de La Recherche Agronomique de Tunisie,Dipartimento Di Medicina Veterinaria
[3] Université de Carthage,undefined
[4] Università Degli Studi Di Sassari,undefined
来源：
Tropical Animal Health and Production | 2023年 / 55卷
关键词：
Morphometric traits; SNP; Haplotype block;
D O I：
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摘要：
The aim of the present study was to evaluate variability and haplotype structure of twenty-eight single nucleotide polymorphisms (SNPs) at myostatin (MSTN), insulin-like growth factor 1 (IGF1), and bone morphogenetic protein 2 (BMP2) genes. Association between the polymorphic SNPs and morphometric traits was performed on a population of 263 Tunisian goats. The SNPs analyzed were all polymorphic (except one), and the three genes had different haplotype structures. Significant association of SNPs at MSTN with head length was highlighted in the Tunisian goats. The variability at IGF1 gene was associated with body length, ear length, tail length, and chest depth. For BMP2, significant association was revealed with chest depth. Significant association was also detected between linkage disequilibrium (LD) block 2 at IGF1 with body length. These findings might play a potential role in gene-assisted programs.
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