Spinal cord compression secondary to extramedullary hematopoiesis in thalassemia intermedia

被引：30

作者：

Coşkun E. ^{[1
]}

Keskin A. ^{[2
]}

Süzer T. ^{[1
]}

Sermez Y. ^{[2
]}

Kildaci T. ^{[1
]}

Tahta K. ^{[1
]}

机构：

[1] Department of Neurosurgery, Pamukkale Univ. School of Medicine, 20100, Denizli

[2] Department of Internal Medicine, Pamukkale Univ. School of Medicine, Denizli

来源：

European Spine Journal | 1998年 / 7卷 / 6期

关键词：

Blood transfusion; Extramedullary hematopoiesis; MRI; Spinal cord; Thalassemia;

D O I：

10.1007/s005860050114

中图分类号：

学科分类号：

摘要：

Extramedullary hematopoiesis associated with thalassemia causing spinal cord compression is an extremely rare event in the course of the disease. Documentation with an imaging technique, such as MRI, is mandatory. A patient with thalassemia intermedia, who developed paraparesis in spite of transfusion, underwent surgical decompression. Rapid neurological improvement was observed postoperatively and this neurological condition was protected with adequate hemoglobin level. Management of these patients remains controversial. Various modes of therapy such as surgical decompression, radiotherapy, and transfusion are discussed and the related literature is reviewed.

引用

页码：501 / 504

页数：3

共 19 条

[1]

Amirjamshidi A., Abbassioun K., Ketabchi S.E., Spinal extradural hematopoiesis in adolescent with thalassemia. Report of two cases and a review of the literature, Childs Nerv Syst, 7, pp. 223-225, (1991)

[2]

Cianciulli P., Sorrentino F., Morino L., Massa A., Sergiacomi G.L., Donate V., Amardori S., Radiotherapy combined with erytropoietin for the treatment of extramedullary hematopoiesis in alloimmunized patient with thalassemia intermedia, Ann Hematol, 72, pp. 379-381, (1996)

[3]

Evrard C., Pichereau D., Alsweis S., Martel B., Galateau F., Houtteville J.P., Benazzo A., Leporrier M., Extramedullary hematopoiesis of thoracic and vertebral intraductal localization. A propos of a case and review of the literature, Ann Chir, 48, pp. 284-293, (1994)

[4]

Gatto I., Terrana V., Biondi L., Compressione sul midollo spinale da proliferazione di midollo osseo nello spazio epidurale in soggetto affetto da mallattia di cooley splenectomizzato, Haematologica, 38, pp. 61-76, (1954)

[5]

Gouliamos A., Dardoufas C., Papailiou I., Kalovidouris A., Vlahos L., Papavasiliou C., Low back pain due to extramedullary hematopoiesis, Neuroradiology, 33, pp. 284-285, (1991)

[6]

Hasssou H., Lawn-Tsao L., Langevin E.R., Lathi E.S., Palek J., Spinal cord compression secondary to extramedullary hematopoiesis: A noninvasive management based on MRI, Am J Hematol, 37, pp. 201-203, (1991)

[7]

Jackson D.V., Randall M.I., Richards F.I.I., Spinal cord compression due to extramedullary hematopoiesis in thalassemia: Long term follow-up after radiotherapy, Surg Neurol, 29, pp. 388-392, (1988)

[8]

Khandelwal N., Malik N., Khosla V.K., Suri S., Spinal cord compression due to epidural extramedullary haematopoiesis in thalassemia, Pediatr Radiol, 22, pp. 70-71, (1992)

[9]

Lau S.K., Chan C.K., Chow Y.Y.N., Cord compression due to extramedullary hematopoiesis in a patient with thalassemia, Spine, 19, pp. 2467-2470, (1994)

[10]

Lee A.C., Chiu W., Tai K.S., Wong V., Peh W.C., Lau Y.L., Hypertransfusion for spinal cord compression secondary to extramedullary hematopoiesis, Pediatr Hematol Oncol, 13, pp. 89-94, (1996)

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