Safety and efficacy of reduced dosage ketoprofen with or without tramadol for long-term treatment of osteoarthritis in dogs: a randomized clinical trial

[1] Schaible H-G(2009)Joint pain Exp Brain Res 196 153-162

[2] Richter F(2016)An update on the pathophysiology of osteoarthritis Ann Phys Rehabil Med 59 333-339

[3] Ebersberger A(1950)The sensitivity and innervation of the articular capsule J Bone Jt Surg 4 193-205

[4] Boettger MK(2009)Central sensitization: a generator of pain hypersensitivity by central neural plasticity J Pain Elsevier Ltd 10 895-926

[5] Vanegas H(2007)Systematic review of clinical trials of treatments for osteoarthritis in dogs J Am Vet Med Assoc 230 514-521

[6] Natura G(2012)Systematic review of efficacy of nutraceuticals to alleviate clinical signs of osteoarthritis J Vet Intern Med 26 448-456

[7] Mobasheri A(2013)Systematic review of nonsteroidal anti-inflammatory drug-induced adverse effects in dogs J Vet Intern Med 27 1011-1019

[8] Batt M(2000)Effect of NSAID administration on creatinine clearance in healthy dogs undergoing anaesthesia and surgery J Small Anim Pract 41 547-550

[9] Kellgren J(2002)Effects of preoperative administration of ketoprofen on whole blood platelet aggregation, buccal mucosal bleeding time, and hematologic indices in dogs undergoing elective ovariohysterectomy J Am Vet Med Assoc 220 1818-1822

[10] Samuel E(2007)Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs Am J Vet Res 68 258-264

[1] Schaible H-G(2009)Joint pain Exp Brain Res 196 153-162

[2] Richter F(2016)An update on the pathophysiology of osteoarthritis Ann Phys Rehabil Med 59 333-339

[3] Ebersberger A(1950)The sensitivity and innervation of the articular capsule J Bone Jt Surg 4 193-205

[4] Boettger MK(2009)Central sensitization: a generator of pain hypersensitivity by central neural plasticity J Pain Elsevier Ltd 10 895-926

[5] Vanegas H(2007)Systematic review of clinical trials of treatments for osteoarthritis in dogs J Am Vet Med Assoc 230 514-521

[6] Natura G(2012)Systematic review of efficacy of nutraceuticals to alleviate clinical signs of osteoarthritis J Vet Intern Med 26 448-456

[7] Mobasheri A(2013)Systematic review of nonsteroidal anti-inflammatory drug-induced adverse effects in dogs J Vet Intern Med 27 1011-1019

[8] Batt M(2000)Effect of NSAID administration on creatinine clearance in healthy dogs undergoing anaesthesia and surgery J Small Anim Pract 41 547-550

[9] Kellgren J(2002)Effects of preoperative administration of ketoprofen on whole blood platelet aggregation, buccal mucosal bleeding time, and hematologic indices in dogs undergoing elective ovariohysterectomy J Am Vet Med Assoc 220 1818-1822

[10] Samuel E(2007)Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs Am J Vet Res 68 258-264