Synthesis of 2,6-bis(fluoroalkyl)-2,6-dihydroxytetrahydro-2H-pyran-3,5-dicarboxylates from aldehydes and fluorinated β-oxo esters in the presence of ionic liquid-K2CO3 as catalytic system

被引：0
作者：
S. G. Zlotin
G. V. Kryshtal’
G. M. Zhdankina
A. V. Ignatenko
Ya. V. Burgart
V. I. Saloutin
O. N. Chupakhin
机构：
[1] Russian Academy of Sciences,Zelinskii Institute of Organic Chemistry
[2] Russian Academy of Sciences,Postovskii Institute of Organic Synthesis, Ural Division
来源：
Russian Journal of Organic Chemistry | 2010年 / 46卷
关键词：
Ionic Liquid; Trifluoromethyl; Dicarboxylates; Heterogeneous Catalytic System; Heptafluoropropyl;
D O I：
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中图分类号：
学科分类号：
摘要：
An efficient procedure has been developed for the synthesis of 4-substituted 2,6-bis(fluoroalkyl)-2,6-dihydroxytetrahydro-2H-pyran-3,5-dicarboxylates by reactions of aldehydes with fluorine-containing β-oxo esters in heterogeneous catalytic system 1-butyl-3-methylimidazolium tetrafluoroborate [bmim][BF4]-K2CO3 activated by ultrasound. The system retains its catalytic activity for three reaction cycles.
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页码：468 / 473
页数：5
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