Oxidation of 5-hydroxy-6-methyluracil with molecular oxygen in the presence of copper(II) chloride in aqueous solution

被引：0

作者：

T. R. Nugumanov

A. V. Antipin

S. A. Grabovskii

N. N. Kabal’nova

Yu. I. Murinov

机构：

[1] Russian Academy of Sciences,Institute of Organic Chemistry, Ufa Research Center

来源：

Russian Journal of General Chemistry | 2011年 / 81卷

关键词：

General Chemistry; Uracil; Molecular Oxygen; Donor Center; Potassium Permanganate;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Oxidation of 5-hydroxy-6-methyluracil with molecular oxygen in the presence of copper(II) chloride involves formation of a 2 : 1 complex with copper(II). The rates of consumption of initial 5-hydroxy-6-methyluracil and oxygen were determined in the temperature range from 40 to 80°C. A probable reaction mechanism implies fixation and activation of molecular oxygen on the copper(II) complex with 5-hydroxy-6-methyluracil with formation of active oxygen species that are responsible for hydroxylation of the double C5=C6 bond in the uracil molecule.

引用

页码：1543 / 1546

页数：3

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