Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population

被引：15
|
作者：
Munang Y.N. [1 ]
Noubiap J.J. [2 ]
Danwang C. [3 ]
Sama J.D. [4 ]
Azabji-Kenfack M. [5 ]
Mbanya J.C. [1 ,6 ,7 ]
Sobngwi E. [1 ,6 ,7 ,8 ]
机构：
[1] Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[2] Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town
[3] Department of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[4] Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[5] Department of Physiology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[6] Laboratory for Molecular Medicine and Metabolism, Biotechnology Center, University of Yaoundé i, Yaoundé
[7] National Obesity Center, Yaoundé Central Hospital, Yaoundé
[8] National Obesity Center, Yaoundé Central Hospital, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé
来源：
BMC Research Notes | / 10卷 / 1期
关键词：
Africa; Cameroon; Gestational diabetes; Oral glucose tolerance test; Reproducibility;
D O I：
10.1186/s13104-017-2944-7
中图分类号：
学科分类号：
摘要：
Objective: To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Results: Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic's 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution. © 2017 The Author(s).
引用
收藏
相关论文
共 50 条
  • [41] Prediction of Gestational Diabetes Mellitus and Pre-diabetes 5 Years Postpartum using 75 g Oral Glucose Tolerance Test at 14-16 Weeks' Gestation
    Lekva, Tove
    Godang, Kristin
    Michelsen, Annika E.
    Qvigstad, Elisabeth
    Normann, Kjersti Ringvoll
    Norwitz, Errol R.
    Aukrust, Pal
    Henriksen, Tore
    Bollerslev, Jens
    Roland, Marie Cecilie Paasche
    Ueland, Thor
    SCIENTIFIC REPORTS, 2018, 8
  • [42] Influence of factors on the results of oral glucose tolerance test screening to diagnose gestational diabetes mellitus
    Basu, A.
    Das Daniel, S.
    Roberts, J.
    Klein, K.
    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2013, 120 : 40 - 40
  • [43] The influence of breastfeeding in postpartum oral glucose tolerance test in women with recent gestational diabetes mellitus
    Dijigow, Fernanda Borges
    Paganoti, Cristiane De Freitas
    Da Costa, Rafaela Alkmin
    Vieira Francisco, Ossana Pulcineli
    Zugaib, Marcelo
    REVISTA BRASILEIRA DE GINECOLOGIA E OBSTETRICIA, 2015, 37 (12): : 565 - 570
  • [44] Hypoglycemia in oral glucose tolerance test in gestational diabetes mellitus screening - is it of any clinical importance?
    Broz, J.
    Rusavy, Z.
    Urbanova, J.
    Nunes, A. M.
    Brunerova, L.
    CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY, 2020, 85 (02): : 131 - 132
  • [45] Efficacy of 50-G Glucose Challenge Test in The Diagnosis of Gestational Diabetes Mellitus
    Inan, Cihan
    Agir, Meric Cagri
    Sagir, Fulya Gokdagli
    HASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKI, 2014, 52 (03): : 181 - 186
  • [46] Effect of fetal hyperinsulinism on oral glucose tolerance test results in patients with gestational diabetes mellitus
    Weiss, PAM
    Scholz, HS
    Haas, J
    Tamussino, KF
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2001, 184 (03) : 470 - 475
  • [47] Oral glucose tolerance test to diagnose gestational diabetes mellitus: Impact of variations in specimen handling
    Jamieson, Emma L.
    Dimeski, Goce
    Flatman, Robert
    Hickman, Peter E.
    Jones, Graham Ross Dallas
    Marley, Julia, V
    McIntyre, H. David
    McNeil, Alan R.
    Nolan, Christopher J.
    Potter, Julia M.
    Sweeting, Arianne
    Ward, Peter
    Horvath, Andrea Rita
    Williams, Paul
    Brown, Greg
    CLINICAL BIOCHEMISTRY, 2023, 115 : 33 - 48
  • [48] Changes in visfatin levels after oral glucose tolerance test in women with gestational diabetes mellitus
    Liang Zhaoxia
    Wu Ying
    Chen Danqing
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2012, 96 (03) : E76 - E79
  • [49] Evaluating the effect of gestational diabetes mellitus on macrosomia based on the characteristics of oral glucose tolerance test
    Bai, Wenlin
    Wang, Hui
    Fang, Ruiling
    Lin, Mengwen
    Qin, Yao
    Han, Hongjuan
    Cui, Jing
    Zhang, Rong
    Ma, Yifei
    Chen, Durong
    Zhang, Wenping
    Wang, Li
    Yu, Hongmei
    CLINICA CHIMICA ACTA, 2023, 544
  • [50] Frequency of impaired oral glucose tolerance test in high risk pregnancies for Gestational Diabetes Mellitus
    Naheed, Farrukh
    Kammeruddin, Karim
    Hashmi, Haleema A.
    Narijo, Sabhagi
    JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2008, 18 (02): : 82 - 85
12345