Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population

被引：15
|
作者：
Munang Y.N. [1 ]
Noubiap J.J. [2 ]
Danwang C. [3 ]
Sama J.D. [4 ]
Azabji-Kenfack M. [5 ]
Mbanya J.C. [1 ,6 ,7 ]
Sobngwi E. [1 ,6 ,7 ,8 ]
机构：
[1] Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[2] Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town
[3] Department of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[4] Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[5] Department of Physiology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé i, Yaoundé
[6] Laboratory for Molecular Medicine and Metabolism, Biotechnology Center, University of Yaoundé i, Yaoundé
[7] National Obesity Center, Yaoundé Central Hospital, Yaoundé
[8] National Obesity Center, Yaoundé Central Hospital, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé
来源：
BMC Research Notes | / 10卷 / 1期
关键词：
Africa; Cameroon; Gestational diabetes; Oral glucose tolerance test; Reproducibility;
D O I：
10.1186/s13104-017-2944-7
中图分类号：
学科分类号：
摘要：
Objective: To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Results: Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic's 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution. © 2017 The Author(s).
引用
收藏
相关论文
共 50 条
  • [1] The 75g simplified oral glucose tolerance test in the diagnosis of gestational diabetes mellitus
    Mercado-Asis, Leilani B.
    Chu, Albert L.
    Mamba, Lucy Anne E.
    Lorenzo, Zarina G.
    Sia-Atanacio, Aileen Y.
    ENDOCRINE JOURNAL, 2010, 57 : S382 - S382
  • [2] The diagnosis of gestational diabetes mellitus (GDM) using a 75 g oral glucose tolerance test: A prospective observational study
    O'Malley, E. G.
    Reynolds, C. M. E.
    O'Kelly, R.
    McMahon, L.
    Sheehan, S. R.
    Turner, M. J.
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2020, 163
  • [3] Diagnosis of gestational diabetes mellitus using a modified 100 g oral glucose tolerance test
    C Phaloprakarn
    S Tangjitgamol
    Journal of Perinatology, 2008, 28 : 7 - 11
  • [4] Diagnosis of gestational diabetes mellitus using a modified 100 g oral glucose tolerance test
    Phaloprakarn, C.
    Tangjitgamol, S.
    JOURNAL OF PERINATOLOGY, 2008, 28 (01) : 7 - 11
  • [5] The effect of hyperemesis gravidarum on the 75g oral glucose tolerance test screening and gestational diabetes mellitus
    Madendag, Y.
    Sahin, E.
    Col, I. Madendag
    Eraslan, Sahin M.
    Tayyar, A. T.
    Ozdemir, F.
    Acmaz, G.
    Senol, V.
    JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2018, 31 (15): : 1989 - 1992
  • [6] The reproducibility of the 75g oral glucose tolerance test
    Dunseath, Gareth
    Mustafa, N.
    Luzio, Stephen D.
    Peter, Rajesh
    Chudleigh, Richard
    Owens, David R.
    DIABETES, 2007, 56 : A406 - A406
  • [7] The Importance of a Postpartum 75 g Oral Glucose Tolerance Test in Women With Gestational Diabetes
    Reinblatt, Shauna L.
    Morin, Lucie
    Meltzer, Sara J.
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA, 2006, 28 (08) : 690 - 694
  • [8] Evaluation of a 1-h 75-g oral glucose tolerance test in the diagnosis of gestational diabetes
    Campos, M. A. A.
    Reichelt, A. A. J.
    Facanha, C.
    Forti, A. C.
    Schmidt, M. I.
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2008, 41 (08) : 684 - 688
  • [9] Screening and Diagnosis of Gestational Diabetes Mellitus Using 75-g Oral Glucose Tolerance Test Following the WHO, ADA, and IADPSG Criteria
    Pineda-Cortel, Maria Ruth B.
    Manalo, Marlo Eduardo M.
    Canivel, Russel Ray C.
    Matias, Reynaldo S., III
    Dizon, Ayla Jania B.
    Bacani, Manuel Nikko S.
    Dalmacio, Juan Severino B.
    JOURNAL OF DIABETES & METABOLISM, 2018, 9 (07)
  • [10] Gestational diabetes mellitus among Sub-Saharan African and Surinamese women in the Netherlands
    Rademaker, D.
    van Schaijik, C. I.
    Oostvogels, A. J. J. M.
    van Rijn, B. B.
    Evers, I.
    DeVries, J. H.
    Agyemang, C.
    Vrijkotte, T. G. M.
    Painter, R. C.
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2020, 168
12345