Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice

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作者
Gowoon Son
Seung-Jun Yoo
Shinwoo Kang
Ameer Rasheed
Da Hae Jung
Hyunjun Park
Bongki Cho
Harry W. M. Steinbusch
Keun-A Chang
Yoo-Hun Suh
Cheil Moon
机构
[1] Daegu Gyeungbuk Institute of Science and Technology (DGIST),Department of Brain & Cognitive Sciences, Graduate School
[2] Maastricht University,School for Mental Health and Neuroscience
[3] Daegu Gyeungbuk Institute of Science and Technology (DGIST),Convergence Research Advanced Centre for Olfaction
[4] Max Planck Research Unit for Neurogenetics,Department of Pharmacology, College of Medicine
[5] Gachon University,undefined
[6] Korea Brain Research Institute,undefined
关键词
Alzheimer’s disease; Olfactory dysfunction; β-amyloid; 5xFAD; Olfactory sensory neuron; Zonal organization; Odor detection test; Ca; imaging; Topographic analysis; Neuronal turnover;
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