Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice

被引：0

作者：

Gowoon Son

Seung-Jun Yoo

Shinwoo Kang

Ameer Rasheed

Da Hae Jung

Hyunjun Park

Bongki Cho

Harry W. M. Steinbusch

Keun-A Chang

Yoo-Hun Suh

Cheil Moon

机构：

[1] Daegu Gyeungbuk Institute of Science and Technology (DGIST),Department of Brain & Cognitive Sciences, Graduate School

[2] Maastricht University,School for Mental Health and Neuroscience

[3] Daegu Gyeungbuk Institute of Science and Technology (DGIST),Convergence Research Advanced Centre for Olfaction

[4] Max Planck Research Unit for Neurogenetics,Department of Pharmacology, College of Medicine

[5] Gachon University,undefined

[6] Korea Brain Research Institute,undefined

来源：

Alzheimer's Research & Therapy | / 13卷

关键词：

Alzheimer’s disease; Olfactory dysfunction; β-amyloid; 5xFAD; Olfactory sensory neuron; Zonal organization; Odor detection test; Ca; imaging; Topographic analysis; Neuronal turnover;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 37 条

[1] Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice
Son, Gowoon
Yoo, Seung-Jun
Kang, Shinwoo
Rasheed, Ameer
Jung, Da Hae
Park, Hyunjun
Cho, Bongki
Steinbusch, Harry W. M.
Chang, Keun-A
Suh, Yoo-Hun
Moon, Cheil
ALZHEIMERS RESEARCH & THERAPY, 2021, 13 (01)
[2] Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice
Bader, Angelika Sabine
Gnaedig, Marius-Uwe
Fricke, Merle
Bueschgens, Luca
Berger, Lena Josefine
Klafki, Hans-Wolfgang
Meyer, Thomas
Jahn, Olaf
Weggen, Sascha
Wirths, Oliver
LIFE-BASEL, 2023, 13 (04):
[3] Region-specific amyloid-β accumulation in transgenic mouse olfactory system with Alzheimer's disease-like pathology
Son, Gowoon
Moon, Cheil
CHEMICAL SENSES, 2021, 46
[4] Jowiseungchungtang Inhibits Amyloid-β Aggregation and Amyloid-β-Mediated Pathology in 5XFAD Mice
Shin, Soo Jung
Jeong, Yu-on
Jeon, Seong Gak
Kim, Sujin
Lee, Seong-kyung
Nam, Yunkwon
Park, Yong Ho
Kim, Dabi
Lee, Youn Seok
Choi, Hong Seok
Kim, Jin-il
Kim, Jwa-Jin
Moon, Minho
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (12)
[5] Aβ Accumulation in Vmo Contributes to Masticatory Dysfunction in 5XFAD Mice
Kim, H. B.
Kim, D.
Kim, H.
Kim, W.
Chung, S.
Lee, S. H.
Kim, H. R.
Oh, S. B.
JOURNAL OF DENTAL RESEARCH, 2021, 100 (09) : 960 - 967
[6] Chronic Administration of Dimebon does not Ameliorate Amyloid-β Pathology in 5xFAD Transgenic Mice
Peters, Owen M.
Shelkovnikova, Tatyana
Tarasova, Tatiana
Springe, Signe
Kukharsky, Michail S.
Smith, Gaynor A.
Brooks, Simon
Kozin, Sergey A.
Kotelevtseve, Yury
Bachurin, Sergey O.
Ninkina, Natalia
Buchman, Vladimir L.
JOURNAL OF ALZHEIMERS DISEASE, 2013, 36 (03) : 589 - 596
[7] Caffeoylquinic Acid Mitigates Neuronal Loss and Cognitive Decline in 5XFAD Mice Without Reducing the Amyloid-β Plaque Burden
Suganuma, Takaya
Hatori, Sena
Chen, Chung-Kuan
Hori, Satoshi
Kanuka, Mika
Liu, Chih-Yao
Tatsuzawa, Chika
Yanagisawa, Masashi
Hayashi, Yu
JOURNAL OF ALZHEIMERS DISEASE, 2024, 99 (04) : 1285 - 1301
[8] A Signal Detection Analysis of Olfactory Learning in 12-Month-Old 5xFAD Mice
Roddick, Kyle M.
Fertan, Emre
Schellinck, Heather M.
Brown, Richard E.
JOURNAL OF ALZHEIMERS DISEASE, 2022, 88 (01) : 37 - 44
[9] Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer
Yoo, Seung-Jun
Lee, Ji-Hye
Kim, So Yeun
Son, Gowoon
Kim, Jae Yeon
Cho, Bongki
Yu, Seong-Woon
Chang, Keun-A
Suh, Yoo-Hun
Moon, Cheil
CELL DEATH & DISEASE, 2017, 8 : e2977 - e2977
[10] Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer
Seung-Jun Yoo
Ji-Hye Lee
So Yeun Kim
Gowoon Son
Jae Yeon Kim
Bongki Cho
Seong-Woon Yu
Keun-A Chang
Yoo-Hun Suh
Cheil Moon
Cell Death & Disease, 2017, 8 : e2977 - e2977

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