Neurogenic Causes of Detrusor Underactivity

被引：27
作者：
Kadow B.T. [1 ]
Tyagi P. [1 ]
Chermansky C.J. [1 ]
机构：
[1] Department of Urology, University of Pittsburgh Medical Center, 300 Halket St, Suite 4710, Pittsburgh, 15213, PA
来源：
Current Bladder Dysfunction Reports | 2015年 / 10卷 / 4期
基金：
美国国家卫生研究院;
关键词：
Detrusor underactivity; Neurogenic bladder; Underactive bladder; Urinary retention;
D O I：
10.1007/s11884-015-0331-6
中图分类号：
学科分类号：
摘要：
Detrusor underactivity (DU) is a poorly understood dysfunction of the lower urinary tract which arises from multiple etiologies. Symptoms of DU are non-specific, and a pressure-flow urodynamic study is necessary to differentiate DU from other conditions such as overactive bladder (OAB) or bladder outlet obstruction (BOO). The prevalence of DU ranges from 10 to 48 %, and DU is most prevalent in elderly males. The pathophysiology underlying DU can be from both neurogenic and non-neurogenic causes. In this article, we review the neurogenic causes of detrusor underactivity, including diabetic bladder dysfunction, spinal cord injury, multiple sclerosis, Parkinson’s disease, cerebrovascular accident, traumatic brain injury, and Fowler’s syndrome. As knowledge about the underlying causes of DU advances, there have been several potential therapeutic approaches proposed to help those who suffer from this condition. © 2015, Springer Science+Business Media New York.
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收藏
页码：325 / 331
页数：6
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