RETRACTED ARTICLE: Pyran Derivatives: Anti-Breast Cancer Activity and Docking Study

被引:0
|
作者
H. Han
Z.-F. Zhang
J.-F. Zhang
B. Zhang
机构
[1] Inner Mongolia University For The Nationalities,Nursing Department
[2] Tongliao City Hospital,undefined
[3] The First Affiliated Hospital of Inner Mongolia University For The Nationalities,undefined
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关键词
pyran; anticancer activity; molecular docking study;
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摘要
Four novel pyran derivatives 1–4 are synthesized and characterized by IR, 1H NMR, HRMS, and single crystal X-ray data. Anticancer activity of the compounds is tested against four human breast cancer cells (HCC1937, HCC70, MDA-MB-436, and BT474) by MTT assay. Molecular docking study supports the biological assay data and suggests that compound 2 has a potential as an anticancer agent.
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页码:2664 / 2668
页数:4
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