RETRACTED ARTICLE: Pyran Derivatives: Anti-Breast Cancer Activity and Docking Study

被引:0
|
作者
H. Han
Z.-F. Zhang
J.-F. Zhang
B. Zhang
机构
[1] Inner Mongolia University For The Nationalities,Nursing Department
[2] Tongliao City Hospital,undefined
[3] The First Affiliated Hospital of Inner Mongolia University For The Nationalities,undefined
来源
关键词
pyran; anticancer activity; molecular docking study;
D O I
暂无
中图分类号
学科分类号
摘要
Four novel pyran derivatives 1–4 are synthesized and characterized by IR, 1H NMR, HRMS, and single crystal X-ray data. Anticancer activity of the compounds is tested against four human breast cancer cells (HCC1937, HCC70, MDA-MB-436, and BT474) by MTT assay. Molecular docking study supports the biological assay data and suggests that compound 2 has a potential as an anticancer agent.
引用
收藏
页码:2664 / 2668
页数:4
相关论文
共 50 条
  • [31] DOCKING, ANTI-BREAST CANCER AND ANTIOXIDANT STUDY OF SOME NEW SULFISOXAZOLE BASED ON CARBOHYDRATE
    Alhaideri, Mohammed Ridha A.
    Zimam, Ezzat H.
    ACTA CHEMICA IASI, 2024, 32 (01) : 33 - 54
  • [32] Design, Synthesis and Anti-breast Cancer Activity of Some Novel Substituted Isoxazoles as Anti-breast Cancer Agent
    Mokale, Santosh N.
    Sakle, Nikhil S.
    Bhavale, Swati A.
    Lokwani, Deepak K.
    Shelke, Vishakha R.
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18 (07) : 1009 - 1015
  • [33] Remarkable anti-breast cancer activity and molecular docking studies of ferrocene tethered pyrimidobenzothiazoles and pyrimidobenzimidazoles
    Bansode, Prakash
    Pore, Dattaprasad
    Tayade, Shivaji
    Patil, Sandeep
    Choudhari, Prafulla
    Rashinkar, Gajanan
    RESULTS IN CHEMISTRY, 2023, 5
  • [34] Synthesis, Anti-Breast Cancer Activity, and Molecular Modeling of Some Benzothiazole and Benzoxazole Derivatives
    Abdelgawad, Mohamed A.
    Belal, Amany
    Omar, Hany A.
    Hegazy, Lamees
    Rateb, Mostafa E.
    ARCHIV DER PHARMAZIE, 2013, 346 (07) : 534 - 541
  • [35] Synthesis, in silico and investigation of anti-breast cancer activity of new diphenyl urea derivatives: Experimental and computational study
    Gomec, Muhammed
    Sayin, Koray
    Ozkaraca, Mustafa
    Ozden, Huseyin
    JOURNAL OF MOLECULAR STRUCTURE, 2022, 1265
  • [36] Synthesis, characterization and anti-breast cancer activities of stachydrine derivatives
    Zeng, Huahui
    Xu, Duanjie
    Song, Yagang
    Tian, Shuo
    Qiao, Jingyi
    Li, Zhanzhan
    Zhao, Lingzhou
    Shi, Hui
    Zhou, Yueyue
    Li, Shuo
    Luo, Ying
    Li, Jiashi
    Miao, Mingsan
    Wu, Xiangxiang
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 259
  • [37] Benzoxazole derivatives as new generation of anti-breast cancer agents
    Omar, A. Mohsen M. E.
    AboulWafa, Omaima M.
    El-Shoukrofy, Mai S.
    Amr, Mai E.
    BIOORGANIC CHEMISTRY, 2020, 96
  • [38] Anti-breast Cancer Potential of Natural and Synthetic Coumarin Derivatives
    Song, Feng
    Huo, Xiankai
    Guo, Zeying
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2021, 21 (18) : 1692 - 1709
  • [39] DESIGN, SYNTHESIS, MOLECULAR DOCKING AND ANTI-BREAST CANCER ACTIVITY OF NOVEL QUINAZOLINONES TARGETING ESTROGEN RECEPTOR α
    Ahmed, Marwa F.
    Youns, Mahmoud
    Belal, Amany
    ACTA POLONIAE PHARMACEUTICA, 2016, 73 (01): : 115 - 127
  • [40] Anti-breast cancer activity of resveratrol encapsulated in liposomes
    Zhao, Y. N.
    Cao, Y. N.
    Sun, J.
    Liang, Z.
    Wu, Q.
    Cui, S. H.
    Zhi, D. F.
    Guo, S. T.
    Zhen, Y. H.
    Zhang, S. B.
    JOURNAL OF MATERIALS CHEMISTRY B, 2020, 8 (01) : 27 - 37