Choroidal vascular analysis in myopic eyes: Evidence of foveal medium vessel layer thinning

被引：22

作者：

Alshareef R.A. ^{[1
]}

Khuthaila M.K. ^{[2
]}

Januwada M. ^{[3
]}

Goud A. ^{[3
]}

Ferrara D. ^{[4
]}

Chhablani J. ^{[3
]}

机构：

[1] Department of Ophthalmology, McGill University, Montreal, QC

[2] Department of Ophthalmology, King Faisal Specialist Hospital and Research Center, Riyadh

[3] Srimati Kanuri Santhamma Retina Vitreous Centre, L. V. Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad, Telangana

[4] Department of Ophthalmology, New England Eye Center, Tufts Medical Center, Boston, MA

来源：

International Journal of Retina and Vitreous | / 3卷 / 1期

关键词：

Choroid; Choroidal vessels; Myopia; Optical coherence tomography;

D O I：

10.1186/s40942-017-0081-z

中图分类号：

学科分类号：

摘要：

Purpose: To analyse morphologic features of the choroid in Non-pathological myopic eyes using spectral-domain (SD) optical coherence tomography (OCT). Methods: Retrospective analysis of enhanced depth SD-OCT images of Non-pathological myopic eyes in comparison with age-matched healthy controls was performed. Choroidal thickness (CT) and large choroidal vessel thickness (LCVT) were measured at the fovea, 750 μm nasally from fovea (N750) and 750 μm temporally (T750) from fovea. Medium choroidal vessel thickness (MCVT) was calculated by subtracting LCVT from CT. Choriocapillaris was encompassed by MCVT, given its reduced thickness. Linear regression analysis evaluated the relationship between age and axial with CT, LCVT and MCVT. Results: The study group comprised 42 eyes of 31 patients (mean age 46.13 ± 15.63; 15 females). Control group included 57 eyes of 34 patients (mean age of 42.3 ± 15.29; 24 females). Mean axial length in myopic eyes and control group was 26.57 ± 1.27 and 23.59 ± 0.99 mm respectively. Myopic eyes showed significant thinning of MCVT and CT at all locations (p < 0.0001) compared to controls, unlike LCVT (p > 0.05). With each decade, thinning of up to 37 μm in CT was noted along with thinning of LCVT (up to 22.6 μm) and MCVT (up to 25 μm). Each mm increase in axial length caused 38.2 μm thinning of choroid along with LCVT (< 10 μm), however, MCVT showed more notable thinning (> 30 μm). Conclusion: Significant thinning of MCVT was noted in non-pathological myopic eyes in comparison to healthy subjects. It appears that MCVT has stronger relationship with age and axial length. © The Author(s) 2017.

引用

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