HLA-DRB1 genes and extraarticular rheumatoid arthritis

被引:0
作者
Jean Roudier
机构
[1] INSERM UMR 639,Assistance Publique, Hôpitaux de Marseille, Rheumatology
[2] Université de la Méditerranée,undefined
[3] La Conception Hospital,undefined
来源
Arthritis Research & Therapy | / 8卷
关键词
Rheumatoid Arthritis; Pericarditis; Shared Epitope; Double Dose; Scleritis;
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摘要
The factors that trigger the development of extraarticular features of rheumatoid arthritis (RA) are still unknown. HLA-DR alleles such as HLA-DR4 and HLA-DR1 are associated with the risk to develop RA. A large scale study from Sweden and the Mayo Clinic suggests that HLA-DR4, but not HLA-DR1, is associated with the risk to develop extraarticular RA.
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[1]  
Turesson C(2005)The impact of Arthritis Res Ther 7 R1386-R1393
[2]  
Schaid DJ(1987)genes on extra-articular disease manifestations in rheumatoid arthritis Arthritis Rheum 30 1205-1213
[3]  
Weyand CM(2001)The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis Arthritis Rheum 44 535-540
[4]  
Jacobsson LTH(1995)Influence of shared epitope negative alleles on genetic susceptibility to rheumatoid arthritis J Rheumatol 22 607-610
[5]  
Goronzy JJ(2004)HLA-DRB1 alleles associated with rheumatoid arthritis in southern France. Absence of extraarticular disease despite expression of the shared epitope Arthritis Rheum 50 3476-3484
[6]  
Petersson IF(undefined)Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis undefined undefined undefined-undefined
[7]  
Sturfelt G(undefined)undefined undefined undefined undefined-undefined
[8]  
Nyhäll-Wåhlin BM(undefined)undefined undefined undefined undefined-undefined
[9]  
Truedsson L(undefined)undefined undefined undefined undefined-undefined
[10]  
Dechant SA(undefined)undefined undefined undefined undefined-undefined