Frequency and determinants for hemorrhagic transformation of posterior cerebral stroke: Posterior ischemic stroke and hemorrhagic transformation

被引：22
作者：
Valentino F. [1 ]
Gentile L. [2 ]
Terruso V. [3 ]
Mastrilli S. [1 ]
Aridon P. [1 ]
Ragonese P. [1 ]
Sarno C. [4 ]
Savettieri G. [1 ]
D'Amelio M. [1 ]
机构：
[1] Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BioNeC), Università degli Studi di Palermo, Via Gaetano La Loggia 1, Palermo
[2] Dipartimento di Neurologia e Psichiatria, Università degli Studi di Roma la Sapienza, Rome
[3] ARNAS Civico, Di Cristina e Benfratelli, Palermo
[4] Azienda Ospedaliera Universitaria Policlinico P. Giaccone, Palermo
来源：
BMC Research Notes | / 10卷 / 1期
关键词：
Epidemiology; Hemorrhagic transformation; Posterior ischemic stroke;
D O I：
10.1186/s13104-017-2889-x
中图分类号：
学科分类号：
摘要：
Background: hemorrhagic transformation is a threatening ischemic stroke complication. Frequency of hemorrhagic transformation differs greatly among studies, and its risk factors have been usually studied in patients with anterior ischemic stroke who received thrombolytic therapy. We evaluated, in a hospital-based series of patients with posterior ischemic stroke not treated with thrombolysis, frequency and risk factors of hemorrhagic transformation. Patients with posterior circulation stroke were seen in our Department during the period January 2004 to December 2009. Demographic and clinical information were collected. We estimated risk for spontaneous hemorrhagic transformation by means of uni- and multivariate logistic regression analyses. Results: 119 consecutive patients were included (73 males, 61.3%). Hemorrhagic transformation was observed in 7 patients (5.9%). Only clinical worsening was significantly associated with hemorrhagic transformation (OR 6.8, 95% CI 1.3-34.5). Conclusions: Our findings indicate that patients with posterior have a low risk of spontaneous hemorrhagic transformation, suggesting that these patients might have greater advantage from intravenous thrombolysis. © 2017 The Author(s).
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