Pulmonary paraganglioid carcinoids and bcl-2 oncoprotein expression

被引:0
|
作者
M. Reěl
I. Friedmann
J. Šimek
V. Chrobok
J. Bukač
L. Plíšková
机构
[1] Charles University School of Medicine,Department of Pathology
[2] Charles University School of Medicine,Department of Thoracic Surgery
[3] Charles University School of Medicine,Department of Head and Neck Surgery
[4] Charles University School of Medicine,Department of Biochemistry
[5] Charles University School of Medicine,Department of Computer Technology Center
[6] Northwick Park Hospital and St. Mark's Hospital,Department of Pathology
关键词
bcl-2 protein; apoptosis; carcinoid; paraganglioma; sustentacular cell;
D O I
10.1007/BF02782607
中图分类号
学科分类号
摘要
Bcl-2 protein immunoreactivity was examined in 10 pulmonary carcinoid tumors with abundant S-100 protein-positive sustentacular cells (SCs) diagnosed as paraganglioid carcinoids. Its positivity in the mentioned tumors was compared with that of neoplasms formed of neuroendocrine cells only (30 pulmonary carcinoids), and with another group of 30 lesions consisting of neuroendocrine and sustentacular elements, i.e., paragangliomas (11 paragangliomas of the glomus caroticum and 9 jugulotympanic paragangliomas [JPTGs]), pheochromocytomas (5 cases), and a rare form of pulmonary tumorlets (PTUs) with a high frequency of SCs (5 cases).
引用
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页码:149 / 155
页数:6
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