Incorporation of Isoniazid into Liposomes with Different Lipid Composition

被引：0
|
作者：
G. M. Sorokoumova
A. A. Selishcheva
N. M. Malikova
A. S. Minina
V. I. Shvets
机构：
[1] M. V. Lomonosov Moscow State University,M. V. Lomonosov Moscow State Academy of Fine Chemical Technology; Biological Faculty
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 137卷
关键词：
phospholipids; liposomes; isoniazid; gel filtration;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Liposomes containing isoniazid were obtained by extrusion of multilamellar phospholipid vesicles containing isoniazid, by ultrasound treatment, and from proliposomes. Optimal conditions for isolation of stable liposomes (200 nm in diameter) and the amount of incorporated isoniazid were determined by varying concentrations of phospholipids and isoniazid and by changing phospholipid composition.
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页码：17 / 19
页数：2
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