Within you, without you: HIV-1 Rev and RNA export

被引:23
作者
Dayton A.I. [1 ]
机构
[1] Ctr. for Biologics Evaluation/Res., Food and Drug Administration
关键词
Nuclear Export Signal; Nucleocytoplasmic Transport; Exon Junction Complex; Ternary Complex Formation; Constitutive Transporter Element;
D O I
10.1186/1742-4690-1-35
中图分类号
学科分类号
摘要
Nucleo-cytoplasmic transport of RNA is one of many cellular pathways whose illumination has progressed hand in hand with understanding of retroviral mechanisms. A recent paper in Cell reports the involvement of an RNA helicase in the pathway by which HIV exports partially spliced and unspliced RNA out of the nucleus. This suggests the ubiquity of RNA helicases in RNA export from the nucleus, and has novel mechanistic implications. © 2004 Dayton; licensee BioMed Central Ltd.
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页数:4
相关论文
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