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Guangzhou Med Univ, Guangdong Engn Res Ctr Oral Restorat & Reconstruct, Dept Periodont, Affiliated Stomatol Hosp,Guangzhou Key Lab Basic &, 195 Dongfeng Rd West, Guangzhou 510182, Peoples R China Guangzhou Med Univ, Guangdong Engn Res Ctr Oral Restorat & Reconstruct, Dept Periodont, Affiliated Stomatol Hosp,Guangzhou Key Lab Basic &, 195 Dongfeng Rd West, Guangzhou 510182, Peoples R China