Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model

Singer M(2016)The third international consensus definitions for sepsis and septic shock (sepsis-3) JAMA. 315 801-810

Deutschman CS(2012)Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes Expert Rev Anti-Infect Ther 10 701-706

Seymour CW(1995)Differences in therapeutic efficacy among cell wall-active antibiotics in a mouse model of gram-negative sepsis J Infect Dis 172 1519-1527

Shankar-Hari M(1984)Kinetics of endotoxin release during antibiotic therapy for experimental gram-negative bacterial sepsis J Infect Dis 150 380-388

Annane D(2018)Dynamics of endotoxin, inflammatory variables, and organ dysfunction after treatment with antibiotics in an Crit Care Med 46 e634-ee41

Bauer M(2014) porcine intensive care sepsis model Infection. 42 521-528

Martin GS(1991)Effect of empiric antibiotic treatment on plasma endotoxin activity in septic patients Scand J Infect Dis 23 745-754

Bucklin SE(1980)Effects of different types and combinations of antimicrobial agents on endotoxin release from gram-negative bacteria: an in-vitro and in-vivo study Jpn J Exp Med 50 35-43

Morrison DC(2000)Liberation of endotoxin from Clin Microbiol Infect 6 74-81

Shenep JL(1995) by addition of antibiotics Infect Immun 63 2236-2242

Singer M(2016)The third international consensus definitions for sepsis and septic shock (sepsis-3) JAMA. 315 801-810

Deutschman CS(2012)Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes Expert Rev Anti-Infect Ther 10 701-706

Seymour CW(1995)Differences in therapeutic efficacy among cell wall-active antibiotics in a mouse model of gram-negative sepsis J Infect Dis 172 1519-1527

Shankar-Hari M(1984)Kinetics of endotoxin release during antibiotic therapy for experimental gram-negative bacterial sepsis J Infect Dis 150 380-388

Annane D(2018)Dynamics of endotoxin, inflammatory variables, and organ dysfunction after treatment with antibiotics in an Crit Care Med 46 e634-ee41

Bauer M(2014) porcine intensive care sepsis model Infection. 42 521-528

Martin GS(1991)Effect of empiric antibiotic treatment on plasma endotoxin activity in septic patients Scand J Infect Dis 23 745-754

Bucklin SE(1980)Effects of different types and combinations of antimicrobial agents on endotoxin release from gram-negative bacteria: an in-vitro and in-vivo study Jpn J Exp Med 50 35-43

Morrison DC(2000)Liberation of endotoxin from Clin Microbiol Infect 6 74-81

Shenep JL(1995) by addition of antibiotics Infect Immun 63 2236-2242