Inhibitory activity of monoamine oxidase by coumarins fromPeucedanum japonicum

被引：0
|
作者：
Dang Thi Lan Huong
Hee Cheol Choi
Tae Cheol Rho
Hyun Sun Lee
Myung Koo Lee
Young Ho Kim
机构：
[1] Chungnam National University,College of Pharmacy
[2] Korea Research Institute of Bioscience and Biotechnology (KRIBB),College of Pharmacy
[3] Chungbuk National University,undefined
来源：
Archives of Pharmacal Research | 1999年 / 22卷
关键词：
Umbelliferae; Coumarins; Monoamine oxidase;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Four coumarins were isolated from chloroform extract of the root ofPeucedanum japonicum and identified as praeruptorin A (1), xanthotoxin (2), psoralen (3) and bergapten (4) on the basis of spectroscopic methods. The inhibitory activities of these coumarins on monoamine oxidase prepared by mouse brain were tested. The IC50 values of them were shown to be 27.4 μM (1), 40.7 μM (2), 35.8 μM (3), and 13.8 μM (4),in vitro.
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页码：324 / 326
页数：2
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