A novel peptide design aids in the expression and its simplified process of manufacturing of Insulin Glargine in Pichia pastoris

被引:0
作者
Partha Hazra
Suma Sreenivas
Krishnamurthy Venkatesan
Mukesh B. Patale
Amarnath Chatterjee
N. Ramprabu
Ajamoddin M. Shaikh
Mutyalasetty Kusumanchi
机构
[1] Science and Technology Innovation Center (SNTI),Biocon Biologics Limited (BBL)
[2] Syngene International Limited (Biocon Group of companies),undefined
来源
Applied Microbiology and Biotechnology | 2021年 / 105卷
关键词
Insulin glargine; Single-chain precursor processing; Downstream processing; Comparative physicochemical characterization of insulin glargine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:3061 / 3074
页数:13
相关论文
共 172 条
[21]  
Cereghino JL(2005)Yeast secretory expression of insulin precursors J Chromatogr B Anal Technol Biomed Life Sci 821 389-399
[22]  
Shi J(1992)Recombinant expression of an insulin-like peptide 3 (INSL3) precursor and its enzymatic conversion to mature human INSL3 TrAC Trends Anal Chem 11 4-186
[23]  
Higgins DR(1983)HPLC and tandem detection to monitor conformational properties of biopharmaceuticals Diabetes Care 6 385-162
[24]  
Dave N(2017)In-process control of insulin production by high-performance liquid chromatography Nat Rev Endocrinol 13 181-1142
[25]  
Hazra P(1990)Human insulin (Novo): chemistry and characteristics J Mol Recognit 3 157-388
[26]  
Khedkar A(2000)Insulin analogues in type 1 diabetes mellitus: getting better all the time Diabetes Care 23 1137-336
[27]  
Manjunath HS(2000)Enzymatic semisynthesis of human insulin: an update Diabetes Care 23 370-11
[28]  
Iyer H(2007)Efficacy and safety of HOE 901 versus NPH insulin in patients with type 1 diabetes. The European Study Group of HOE 901 in type 1 diabetes Mass Spectrom Rev 26 327-6770
[29]  
Suryanarayanan S(2015)Basal insulin glargine (HOE 901) versus NPH insulin in patients with type 1 diabetes on multiple daily insulin regimens. U.S. Insulin Glargine (HOE 901) Type 1 Diabetes Investigator Group Appl Microbiol Biotechnol 99 3-717
[30]  
Given BD(2011)Applications of mass spectrometry for the structural characterization of recombinant protein pharmaceuticals Methods Mol Biol (Clifton, NJ) 768 6766-31