Surface plasmon resonance biosensor for the ultrasensitive detection of bisphenol A

被引：0
作者：
Chadtová Song Xue
Gedeonová Erika
Homola Jiří
机构：
[1] Czech Academy of Sciences,Institute of Photonics and Electronics
来源：
Analytical and Bioanalytical Chemistry | 2019年 / 411卷
关键词：
Bisphenol A; Surface plasmon resonance biosensor; Binding inhibition assay; Functionalized gold nanoparticles;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Bisphenol A (BpA) is a chemical that is extensively used in common plastic products, such as food and drink containers. It can leach from the plastics and penetrate into the human body, where it acts as an endocrine disruptor with significant risks to human health. In order to minimize the exposure of human populations to BpA, methods for the detection of BpA are needed. In this work, we present a novel surface plasmon resonance (SPR) biosensor for ultrasensitive detection of BpA. Our approach combines a binding inhibition assay with functionalized gold nanoparticles for the enhancement of sensor response. We demonstrate that the developed biosensor enables the detection of BpA in a wide range of concentrations (0.01 to 100,000 ng/mL) with an extremely low limit of detection—5.2 pg/mL.
引用
收藏
页码：5655 / 5658
页数：3
相关论文
共 55 条
  • [1] Carwile JL(2009)Polycarbonate bottle use and urinary bisphenol A concentrations Environ Health Perspect 117 1368-1372
  • [2] Luu HT(2003)Increased migration levels of bisphenol A from polycarbonate baby bottles after dishwashing, boiling and brushing AU - Brede, C. Food Addit Contam. 20 684-689
  • [3] Bassett LS(2018)Bisphenol A: food exposure and impact on human health Compr Rev Food Sci Food Saf 17 1503-1517
  • [4] Driscoll DA(2016)Recent advances and progress in the detection of bisphenol A Anal Bioanal Chem 408 6913-6927
  • [5] Yuan C(2014)A reusable evanescent wave immunosensor for highly sensitive detection of bisphenol A in water samples Sci Rep 4 5313-5320
  • [6] Chang JY(2018)Sensitive detection of bisphenol A in drinking water and river water using an upconversion nanoparticles-based fluorescence immunoassay in combination with magnetic separation Anal Methods 10 2850-2856
  • [7] Fjeldal P(2018)Real-time and label-free detection of bisphenol A by an ssDNA aptamer sensor combined with dual polarization interferometry New J Chem 42 1963-1966
  • [8] Skjevrak I(2010)Detection of bisphenol A using a novel surface plasmon resonance biosensor Anal Bioanal Chem 398 2869-2875
  • [9] Herikstad H(2012)Biofunctionalized gold nanoparticles for SPR-biosensor-based detection of CEA in blood plasma Anal Bioanal Chem 404 7265-7269
  • [10] Almeida S(2016)Surface plasmon resonance biosensor for detection of pregnancy associated plasma protein A2 in clinical samples Anal Bioanal Chem 408 588-591
123456