PET-CT in Early Detection of Alzheimer’s Disease: A Case Report

被引：0

作者：

Prokopenko S.V. ^{[1
]}

Barankin B.V. ^{[2
]}

Mar’ina N.M. ^{[2
]}

Mozheyko E.Y. ^{[1
]}

Bezdenezhnykh A.F. ^{[1
]}

Koryagina T.D. ^{[1
]}

Chanchikova N.G. ^{[2
]}

Tokarev N.A. ^{[2
]}

Karlova E.A. ^{[2
]}

Ozerskaya A.V. ^{[2
]}

Badrin E.A. ^{[2
]}

Belugin K.V. ^{[2
]}

Savel’eva A.A. ^{[2
]}

Shepelevich N.V. ^{[2
]}

机构：

[1] Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky, Krasnoyarsk

[2] Federal Siberian Research Clinical Center, Krasnoyarsk

来源：

Human Physiology | 2018年 / 44卷 / 8期

关键词：

Alzheimer’s disease; early detection; positron-emission tomography;

D O I：

10.1134/S0362119718080108

中图分类号：

学科分类号：

摘要：

Abstract: The article describes a clinical case of a female patient with Alzheimer’s disease at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologist by her husband who was concerned by the patient’s family history (his mother-in-law suffered from Alzheimer’s disease) and some memory problems that his wife had recently encountered. The diagnosis was suspected based on the results of neuropsychological evaluation of cognitive functions corresponding to mild cognitive impairment. To confirm the presence of a neurodegenerative disease, brain positron-emission tomography with F-18 fluorodesoxyglucose (FDG) was performed. Hypometabolism of the radio-tracer was detected in the cortex of temporal and parietal lobes, in the association cortex of the left temporal and the right occipital lobes, and in the posterior part of the left cyngulate gyrus. These findings correlated with the patient’s cognitive evaluation and thus provided the nosological diagnosis at an early stage of the disease. © 2018, Pleiades Publishing, Inc.

引用

页码：864 / 868

页数：4

共 14 条

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