Expression of Semaphorin CD100 on Peripheral Blood Lymphocytes from Patients with Remitting Multiple Sclerosis

被引：0
作者：
Trushnikova T.N. [1 ]
Baidina T.V. [1 ]
Danchenko I.Y. [1 ]
Kuklina E.M. [2 ]
Nekrasova I.V. [2 ]
机构：
[1] Vagner Perm State Medical Academy, Perm
[2] Institute of Microbial Ecology and Genetics, Urals Branch, Russian Academy of Sciences, Perm
来源：
Neuroscience and Behavioral Physiology | 2015年 / 45卷 / 3期
关键词：
CD72; multiple sclerosis; semaphorin CD100; T lymphocytes;
D O I：
10.1007/s11055-015-0077-9
中图分类号：
学科分类号：
摘要：
The expression of semaphorin CD100 by intact peripheral blood T lymphocytes from patients with multiple sclerosis (MS) not receiving immunomodulatory treatment was studied. Cellular CD100 expression levels were assessed, along with levels of CD72 receptor-carrying B lymphocytes. Significant differences were seen between the levels of CD100 expression in patients with MS and healthy donors. These data suggest the possibility of using semaphorin as a potential target for actions on MS-associated pathological inflammatory processes. © 2015, Springer Science+Business Media New York.
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页码：338 / 341
页数：3
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