Synthesis of 4,6-bis(1H-1,2,3-triazolyl)pyrimidines by the reaction of 4,6-diazido-2-(4-methoxyphenyl)pyrimidine with compounds containing a reactive methylene group

被引：0

作者：

Nikolaenkova E.B. ^{[1
]}

Krivopalov V.P. ^{[1
]}

机构：

[1] Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences

来源：

Chemistry of Heterocyclic Compounds | 1997年 / 33卷 / 8期

关键词：

Methylene; Ester; Organic Chemistry; Pyrimidine; Triethylamine;

D O I：

10.1007/BF02253171

中图分类号：

学科分类号：

摘要：

The reaction of 4,6-diazido-2-(4-methoxyphenyl)pyrimidine with cyanoacetic ester in the presence of triethylamine leads only to 4-azido-6-amino-1-(4-methoxyphenyl)pyrimidine. The main product in reactions with 1,3-dicarbonyl compounds (acetylacetone, acetoacetic and benzoylacetic esters) is the corresponding substituted 4,6-bis(1H-1,2,3-triazolyl)pyrimidine. Theformation of4-azido-6-(1H-1,2,3-triazolyl)pyrimidine and4-amino-6-(1H-1,2,3-triazolyl)pyrimidine as minor products was also recorded. ©1998 Plenum Publishing Corporation.

引用

页码：968 / 972

页数：4

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