NK cells of the oldest seniors represent constant and resistant to stimulation high expression of cellular protective proteins SIRT1 and HSP70

被引:0
作者
Lucyna Kaszubowska
Jerzy Foerster
Jan Jacek Kaczor
Daria Schetz
Tomasz Jerzy Ślebioda
Zbigniew Kmieć
机构
[1] Medical University of Gdańsk,Department of Histology
[2] Medical University of Gdańsk,Department of Social and Clinical Gerontology
[3] Medical University of Gdańsk,Department of Bioenergetics and Physiology of Exercise
[4] Medical University of Gdańsk,Department of Pharmacology
来源
Immunity & Ageing | / 15卷
关键词
NK cells; Ageing; Adaptive stress response; SIRT1; HSP70; SOD2; Isoprostanes; Carbonyl groups; Oxidative stress; Innate immunity;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 374 条
[1]  
Artis D(2015)The biology of innate lymphoid cells Nature 517 293-301
[2]  
Spits H(2016)Innate lymphoid cells in defense, immunopathology and immunotherapy Nat Immunol 17 755-757
[3]  
Cording S(2011)Molecular mechanisms of natural killer cell activation J Innate Immun. 3 216-226
[4]  
Medvedovic J(2013)The impact of ageing on natural killer cell function and potential consequences for health in older adults Ageing Res Rev 12 1069-1078
[5]  
Aychek T(2014)Immunological memory within the innate immune system EMBO J 33 1295-1303
[6]  
Eberl G(2011)Innate or adaptive immunity? The example of natural killer cells Science 331 44-49
[7]  
Bryceson YT(2011)Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation Proc Natl Acad Sci U S A 108 728-732
[8]  
Chiang SCC(2010)Regulation of human NK-cell cytokine and chemokine production by target cell recognition Blood 115 2167-2176
[9]  
Darmanin S(2002)Chemokine production by natural killer cells from nonagenarians Eur J Immunol 32 1524-1529
[10]  
Fauriat C(2000)IL-2 activation of NK cells: involvement of MKK1/2/ERK but not p38 kinase pathway J Immunol 164 6244-6251