Heracleum moellendorffii roots inhibit the production of pro-inflammatory mediators through the inhibition of NF-κB and MAPK signaling, and activation of ROS/Nrf2/HO-1 signaling in LPS-stimulated RAW264.7 cells

被引:0
作者
Ha Na Kim
Jeong Dong Kim
Joo Ho Yeo
Ho-Jun Son
Su Bin Park
Gwang Hun Park
Hyun Ji Eo
Jin Boo Jeong
机构
[1] Andong National University,Department of Medicinal Plant Resources
[2] National Institute of Forest Science,Forest Medicinal Resources Research Center
[3] Andong National University,Insititute of Agricultural Science and Technology
来源
BMC Complementary and Alternative Medicine | / 19卷
关键词
Anti-inflammation; Inflammatory diseases; Inflammatory response;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 191 条
  • [11] Guo XY(2012)The role of cyclooxygenases in inflammation, cancer, and development Immunol Rev 246 202-212
  • [12] Liu LJ(2007)Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E2 Nat Rev Immunol 7 911-260
  • [13] Huang YN(2018)Macrophages in inflammation Front Pharmacol 9 225-10930
  • [14] OuYang XK(1998)NF-kappaB and the link between inflammation and cancer Annu Rev Immunol 16 10925-85
  • [15] Qu YL(1997)MAPK phosphatases--regulating the immune response Proc Natl Acad Sci U S A 94 79-530
  • [16] Alam MB(2009)Activation of Nrf2/HO-1 pathway by Nardochinoid C inhibits inflammation and oxidative stress in lipopolysaccharide-stimulated macrophages Ethnopharmacol. 121 524-858
  • [17] Seo BJ(2011)NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses J Ethnopharmacol 133 850-2511
  • [18] Zhao P(2010)Reduced stress defense in heme oxygenase 1-deficient cells Int Immunopharmacol 10 2499-379
  • [19] Lee SH(2003)Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide. J Curr Pharm Des 9 371-516
  • [20] Bang JE(2011)Anti-inflammatory action of methanol extract of Biochem Pharmacol 82 510-261