Acute Effect of Intravenous Sildenafil on Cerebral Blood Flow in Patients with Vasospasm After Subarachnoid Hemorrhage

[1] Macdonald RL(2014)Delayed neurological deterioration after subarachnoid haemorrhage Nat Rev Neurol 10 44-58

[2] Etminan N(2011)Effect of pharmaceutical treatment on vasospasm, delayed cerebral ischemia, and clinical outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis J Cereb Blood Flow Metab 31 1443-1451

[3] Vergouwen MDI(2011)Endothelial nitric oxide synthase mediates endogenous protection against subarachnoid hemorrhage-induced cerebral vasospasm Stroke 42 776-782

[4] Ilodigwe D(2006)Systemic administration of phosphodiesterase V inhibitor, sildenafil citrate, for attenuation of cerebral vasospasm after experimental subarachnoid hemorrhage Neurosurgery 59 1102-1107

[5] MacDonald RL(2010)The effect of the sildenafil citrate on cerebral vasospasm and apoptosis following experimental subarachnoid hemorrhage in rats J Neurosurg Sci 54 29-37

[6] Vellimana AK(2012)Phosphodiesterase 5 inhibition attenuates cerebral vasospasm and improves functional recovery after experimental subarachnoid hemorrhage Neurosurgery 70 178-186

[7] Milner E(2015)A Phase I proof-of-concept and safety trial of sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage J Neurosurg 110 1-10

[8] Azad TD(1983)Brain blood flow measured with intravenous H J Nucl Med 24 790-798

[9] Atalay B(2009)(15)O. II. Implementation and validation Stroke 40 3039-3044

[10] Caner H(2012)Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage Stroke 43 1788-1794

[1] Macdonald RL(2014)Delayed neurological deterioration after subarachnoid haemorrhage Nat Rev Neurol 10 44-58

[2] Etminan N(2011)Effect of pharmaceutical treatment on vasospasm, delayed cerebral ischemia, and clinical outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis J Cereb Blood Flow Metab 31 1443-1451

[3] Vergouwen MDI(2011)Endothelial nitric oxide synthase mediates endogenous protection against subarachnoid hemorrhage-induced cerebral vasospasm Stroke 42 776-782

[4] Ilodigwe D(2006)Systemic administration of phosphodiesterase V inhibitor, sildenafil citrate, for attenuation of cerebral vasospasm after experimental subarachnoid hemorrhage Neurosurgery 59 1102-1107

[5] MacDonald RL(2010)The effect of the sildenafil citrate on cerebral vasospasm and apoptosis following experimental subarachnoid hemorrhage in rats J Neurosurg Sci 54 29-37

[6] Vellimana AK(2012)Phosphodiesterase 5 inhibition attenuates cerebral vasospasm and improves functional recovery after experimental subarachnoid hemorrhage Neurosurgery 70 178-186

[7] Milner E(2015)A Phase I proof-of-concept and safety trial of sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage J Neurosurg 110 1-10

[8] Azad TD(1983)Brain blood flow measured with intravenous H J Nucl Med 24 790-798

[9] Atalay B(2009)(15)O. II. Implementation and validation Stroke 40 3039-3044

[10] Caner H(2012)Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage Stroke 43 1788-1794