Multimodal imaging in choroidal osteoma

被引:15
作者
Olguin-Manríquez F. [1 ,2 ]
Enríquez A.B. [1 ,2 ]
Crim N. [1 ,2 ]
Meraz-Gutierrez M. [1 ]
Soberón-Ventura V. [1 ,2 ]
Ávila I. [1 ]
Morales-Canton V. [1 ,2 ]
Jimenez-Sierra J.M. [1 ,2 ]
机构
[1] 'Dr. Luis Sánchez Bulnes' Hospital, Asociación Para Evitar la Ceguera en México I.A.P, Vicente García Torres 46, Coyoacón, Mexico City
[2] Retina Department, Dr. Luis Sánchez Bulnes' Hospital, Asociación Para Evitar la Ceguera en México I.A.P, Mexico City
关键词
Choroidal excavation; Choroidal neovascularization; Choroidal osteoma; EDI-OCT; OCT-A; Ultra-widefield retinal imaging;
D O I
10.1186/s40942-018-0132-0
中图分类号
学科分类号
摘要
Purpose: To describe characteristics of choroidal osteomas (CO), using ocular ultrasound, fluorescein angiography, ultra-widefield retinal imaging, ultra-widefield autofluorescence, optical coherence tomography, enhanced-depthimaging OCT, and OCT angiography (OCT-A). Methods: Retrospective, observational case series study. Clinical records from patients with diagnosis of CO who underwent complete imaging evaluation were analyzed. Results: Sixteen eyes from 11 patients were included. Mean patient age was 33.4 years (range 20-61), 72.7% were female, 100% were Hispanic, and 54.5% had unilateral CO. Median visual acuity was 20/150 (range 20/20-2000). CO was completely calcified in 25%, partially decalcified in 50%, and decalcified in 25%. Other features included choroidal neovascularization (18.75%), focal choroidal excavation (12.5%), choroidal depression associated to decalcification (18.75%), thinning of outer retina and photoreceptor layers over decalcified tumor (75%). Decreased fluorescence on FAF was observed in decalcified regions while relatively preserved fluorescence was observed in calcified regions. Conclusions: Nowadays, diagnostic tests provide important information about each stage of choroidal osteoma. Progressive decalcification of the tumor might have a common pathogenic role for development of FCE or choroidal depression. OCT-A/FA proved to be valuable tools for detection of CNV in patients with CO. © 2019 The Author(s).
引用
收藏
相关论文
共 17 条
  • [1] Shields C.L., Shields J.A., Augsburger J.J., Choroidal osteoma, Surv Ophthalmol., 33, pp. 17-27, (1988)
  • [2] Shields J.A., Shields C.L., Atlas of Intraocular Tumors, (1988)
  • [3] Shields J.A., Shields C.L., Osseous tumors of the uvea, Intraocular Tumors: A Text and Atlas, pp. 261-272, (1992)
  • [4] Garcia Y., Lasierra R., Pina J.I., Madariaga B., Osteoma Coroideo. Una inusual forma de calcificación del globo ocular, Radiología, 42, 5, pp. 331-333, (2000)
  • [5] Alameddine R.M., Mansour M., Kahtani E., Review of choroidal osteomas, Middle East Afr J Ophthalmol., 21, 3, pp. 244-250, (2014)
  • [6] Shields C.L., Sun H., Demirci H., Shields J.A., Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma, Arch Ophthalmol., 123, 12, pp. 1658-1666, (2005)
  • [7] Trattler W., Kaiser P.K., Friedman N.J., Review of Ophthalmology, (2012)
  • [8] Erol M.K., Coban D.T., Ceran B.B., Bulut M., Enhanced depth imaging optical coherence tomography and fundus autofluorescence findings in bilateral choroidal osteoma: A case report, Arq Bras Oftalmol., 76, 3, pp. 189-191, (2013)
  • [9] Shields C.L., Arepalli S., Atalay H.T., Ferenczy S.R., Fulco E., Shields J.A., Choroidal osteoma shows bone lamella and vascular channels on enhanced depth imaging optical coherence tomography in 15 eyes, Retina, 35, 4, pp. 750-757, (2015)
  • [10] Cennamo G., Romano M.R., Breve M.A., Velotti N., Reibaldi M., De Crecchio G., Evaluation of choroidal tumors with optical coherence tomography: Enhanced depth imaging and OCT-angiography features, Eye, 31, 6, pp. 906-915, (2017)