Identification of bio-active secondary metabolites from Actinobacteria as potential drug targets against Porphyromonas gingivalis in oral squamous cell carcinoma using molecular docking and dynamics study

[1] Azman AS(2019)Actinobacteria-a promising natural source of anti-biofilm agents Int Microbiol 22 403-409

[2] Mawang CI(2021)Medicinal applications and molecular targets of dequalinium chloride Biochem Pharmacol 186 362-26

[3] Khairat JE(2018)Prediction is a balancing act: importance of sampling methods to balance sensitivity and specificity of predictive models based on imbalanced chemical data sets Front Chem 6 1-22623

[4] AbuBakar S(2005)Bioactive microbial metabolites J Antibiot 58 22613-9

[5] Bailly C(2015)Periodontal pathogens Porphyromonasgingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model Oncotarget 6 1-1440

[6] Banerjee P(2012)Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen FEMS Microbiol Lett 333 1430-378

[7] Dehnbostel FO(2019)Recombinant fimbriae protein of Porphyromonas gingivalis induces an inflammatory response via the TLR4/NF-κB signaling pathway in human peripheral blood mononuclear cells Int J Mol Med 43 1533033819867354-250

[8] Preissner R(2019)Role of oral microbiome signatures in diagnosis and prognosis of oral cancer Technol Cancer Res Treat 18 370-32302

[9] Bérdy J(2014)Porphyromonas gingivalis-induced autophagy suppresses cell proliferation through G1 arrest in oral cancer cells Arch Oral Biol 59 42717-218

[10] Binder Gallimidi A(2022)Proteolytic activity-independent activation of the immune response by gingipains from mBio 13 243-3898

[1] Azman AS(2019)Actinobacteria-a promising natural source of anti-biofilm agents Int Microbiol 22 403-409

[2] Mawang CI(2021)Medicinal applications and molecular targets of dequalinium chloride Biochem Pharmacol 186 362-26

[3] Khairat JE(2018)Prediction is a balancing act: importance of sampling methods to balance sensitivity and specificity of predictive models based on imbalanced chemical data sets Front Chem 6 1-22623

[4] AbuBakar S(2005)Bioactive microbial metabolites J Antibiot 58 22613-9

[5] Bailly C(2015)Periodontal pathogens Porphyromonasgingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model Oncotarget 6 1-1440

[6] Banerjee P(2012)Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen FEMS Microbiol Lett 333 1430-378

[7] Dehnbostel FO(2019)Recombinant fimbriae protein of Porphyromonas gingivalis induces an inflammatory response via the TLR4/NF-κB signaling pathway in human peripheral blood mononuclear cells Int J Mol Med 43 1533033819867354-250

[8] Preissner R(2019)Role of oral microbiome signatures in diagnosis and prognosis of oral cancer Technol Cancer Res Treat 18 370-32302

[9] Bérdy J(2014)Porphyromonas gingivalis-induced autophagy suppresses cell proliferation through G1 arrest in oral cancer cells Arch Oral Biol 59 42717-218

[10] Binder Gallimidi A(2022)Proteolytic activity-independent activation of the immune response by gingipains from mBio 13 243-3898