Antioxidant, anti-inflammatory activity, and phytochemical constituents of ficus (Ficus amplissima Smith) bark

被引：0
作者：
Rajan Murugan
Karuppusamy Arunachalam
Thangaraj Parimelazhagan
机构：
[1] Bharathiar University,Bioprospecting Laboratory, Department of Botany
来源：
Food Science and Biotechnology | 2012年 / 21卷
关键词：
antioxidant; anti-inflammatory; Lup-20(29)-en-3-yl acetate; lupeol;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In the present investigation, phenolics (36.6 g gallic acid equivalents (GAE)/100 g extract), tannin (21.6 g GAE/100 g extract), and flavonoid content (67.5 g rutin equivalents/100 g extract) were found to be highest in acetone extract. Ficus (Ficus amplissima) acetone extract showed maximum antioxidant activity in phosphomolybdenum (958.8 mg ascorbic acid equivalents/g extract), DPPH (1.6 μg/mL), ferric reducing antioxidant power (2,993 mmol Fe (II)/g extract), and metal chelating (39.7 mg EDTA equivalents/g extract) assays. In anti-inflammatory study, 400 mg/kg acetone extract showed maximum reduction in the paw volume compare to indomethacin. GC-MS analysis indicated that bark contain rich source of non-polar compounds like Lup-20(29)-en-3-yl acetate (33.04%). Hence, Ficus can be valuable source for antioxidant and anti-inflammatory and seemed to be applicable in medicine.
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页码：59 / 67
页数：8
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