Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.

被引:0
作者
Yu. V. Nesterova
T. N. Povet’eva
L. N. Zibareva
N. I. Suslov
E. P. Zueva
S. G. Aksinenko
O. G. Afanas’eva
S. G. Krylova
E. N. Amosova
O. Yu. Rybalkina
K. A. Lopatina
机构
[1] Tomsk National Research Medical Center,E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
[2] National Research Tomsk State University,undefined
来源
Bulletin of Experimental Biology and Medicine | 2017年 / 163卷
关键词
anti-inflammatory and analgesic activities; flavonoids;
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摘要
Anti-inflammatory and analgesic activities of the complex of flavonoids from Lychnis chalcedonica L. were studied in the models of acute aseptic inflammation induced by carrageenan, histamine, and serotonin and acetic acid-induced painful chemical stimulation. It is demonstrated that course treatment with flavonoids derived from Lychnis chalcedonica L. produced a stable pharmacological effect comparable with that of the reference anti-inflammatory drug diclofenac.
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页码:222 / 225
页数:3
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