The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets

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作者
Torsten Lowin
Georg Pongratz
Rainer H. Straub
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[1] University Hospital Duesseldorf,Funktionsbereich & Hiller Forschungszentrum für Rheumatologie, Life Science Center
[2] University Hospital of Regensburg,Laboratory of Experimental Rheumatology and Neuroendocrine Immunology
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Cannabinoid; Synovial fibroblasts; Cytokines; MMP; Proliferation; Arthritis;
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