Reference and human biomonitoring (HBM) values on the basis of tolerable intake amounts. Part III: HBM value for di(2-ethylhexyl)phthalate (DEHP) [Ableitung von human-biomonitoring-(HBM-)werten auf der basis tolerabler aufnahmemengen. Teil III: HBM-werte für di(2-ethylhexyl)phthalat (DEHP): Stellungnahme der kommission human-biomonitoring des umweltbundesamtes]

[1] Wichert Grande S., Andrade A.J.M., Talsness C.E., Et al., A dose-response study following in utero and lactational exposure to Di(2-ethylhexyl)phthalate: Effects on female rat, reproductive development, Toxicol Sci, 91, 1, pp. 247-254, (2006)

[2] Koch H.M., Gonzalez-Reche L.M., Angerer J., On-line cleanup by multidimensional LC-ESI-MS/MS for high throughput quantification of primary and secondary phthalate metabolites in human urine, J Chromatogr B, 784, pp. 169-182, (2003)

[3] Koch H.M., Drexler H., Angerer J., An estima tion of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population, Int J Hyg Environ Health, 206, pp. 1-17, (2003)

[4] Koch H.M., Drexler H., Angerer J., Die innere Belastung der Allgemeinbevölkerung mit Di(2- ethylhexyl)phthalat (DEHP), Umweltmed Forsch Prax, 8, pp. 15-23, (2003)

[5] Poon R., Lecavallier P., Mueller P., Et al., Subchronic oral toxicity of di-n-octylphthalate and di(2-ethylhexyl)phthalate in the rat, Food Chem Toxicol, 35, pp. 225-239, (1997)

[6] Hassauer M., Schneider K., Schuhmacher-Wolz U., Bericht zum F+E-Vorhaben 201 61 214 "Aktualisierung von TRD (Tolerierbare Resorbierte Dosis)-Werte- und Prüfwertebegründungen für den Direktpfad Boden/Mensch gemäß der Bundesbodenschutz- und Altlastenverordnung, Im Auftrag des Umweltbundesamtes - Umweltforschungsplan des Bundesministers für Umwelt, Naturschutz und Reaktorsicherheit, (2003)

[7] Ecotoxicity and the Environment (CSTEE) (1998) Opinion on Phthalate migration from soft PVC toys and childcare articles - Data made available since the 16th of June 1998, opinion expressed at the 6th CSTEE plenary meeting, Brussels, 26/27, (1998)

[8] Dirven H.A., van den Broek P.H., Jongeneelen F.J., Determination of four metabolites of the plasticizer di(2-ethylhexyl)phthalate in human urine samples, Int Arch Occup Environ Health, 64, 8, pp. 555-560, (1993)

[9] Koch H.M., Bolt H.M., Angerer J., Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single dose of deuterium-labelled DEHP, Arch Toxicol, 78, pp. 123-130, (2004)

[10] Koch H.M., Bolt H.M., Preuss R., Angerer J., New metabolites of Di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium labelled DEHP, Arch Toxicol, 79, pp. 367-376, (2005)

[1] Wichert Grande S., Andrade A.J.M., Talsness C.E., Et al., A dose-response study following in utero and lactational exposure to Di(2-ethylhexyl)phthalate: Effects on female rat, reproductive development, Toxicol Sci, 91, 1, pp. 247-254, (2006)

[2] Koch H.M., Gonzalez-Reche L.M., Angerer J., On-line cleanup by multidimensional LC-ESI-MS/MS for high throughput quantification of primary and secondary phthalate metabolites in human urine, J Chromatogr B, 784, pp. 169-182, (2003)

[3] Koch H.M., Drexler H., Angerer J., An estima tion of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population, Int J Hyg Environ Health, 206, pp. 1-17, (2003)

[4] Koch H.M., Drexler H., Angerer J., Die innere Belastung der Allgemeinbevölkerung mit Di(2- ethylhexyl)phthalat (DEHP), Umweltmed Forsch Prax, 8, pp. 15-23, (2003)

[5] Poon R., Lecavallier P., Mueller P., Et al., Subchronic oral toxicity of di-n-octylphthalate and di(2-ethylhexyl)phthalate in the rat, Food Chem Toxicol, 35, pp. 225-239, (1997)

[6] Hassauer M., Schneider K., Schuhmacher-Wolz U., Bericht zum F+E-Vorhaben 201 61 214 "Aktualisierung von TRD (Tolerierbare Resorbierte Dosis)-Werte- und Prüfwertebegründungen für den Direktpfad Boden/Mensch gemäß der Bundesbodenschutz- und Altlastenverordnung, Im Auftrag des Umweltbundesamtes - Umweltforschungsplan des Bundesministers für Umwelt, Naturschutz und Reaktorsicherheit, (2003)

[7] Ecotoxicity and the Environment (CSTEE) (1998) Opinion on Phthalate migration from soft PVC toys and childcare articles - Data made available since the 16th of June 1998, opinion expressed at the 6th CSTEE plenary meeting, Brussels, 26/27, (1998)

[8] Dirven H.A., van den Broek P.H., Jongeneelen F.J., Determination of four metabolites of the plasticizer di(2-ethylhexyl)phthalate in human urine samples, Int Arch Occup Environ Health, 64, 8, pp. 555-560, (1993)

[9] Koch H.M., Bolt H.M., Angerer J., Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single dose of deuterium-labelled DEHP, Arch Toxicol, 78, pp. 123-130, (2004)

[10] Koch H.M., Bolt H.M., Preuss R., Angerer J., New metabolites of Di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium labelled DEHP, Arch Toxicol, 79, pp. 367-376, (2005)