Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis

被引：0

作者：

Yuriy Pomeshchik

Erika Velasquez

Jeovanis Gil

Oxana Klementieva

Ritha Gidlöf

Marie Sydoff

Silvia Bagnoli

Benedetta Nacmias

Sandro Sorbi

Gunilla Westergren-Thorsson

Gunnar K. Gouras

Melinda Rezeli

Laurent Roybon

机构：

[1] BMC D10,iPSC Laboratory for CNS Disease Modelling, Department of Experimental Medical Science

[2] Lund University,Strategic Research Area MultiPark

[3] Lund University,Lund Stem Cell Center

[4] Lund University,Clinical Protein Science & Imaging, Department of Biomedical Engineering

[5] BMC D13,Medical Micro

[6] Lund University,Spectroscopy, Department of Experimental Medical Science

[7] BMC B10,Lund University BioImaging Centre, Faculty of Medicine

[8] Lund University,Laboratorio Di Neurogenetica, Dipartimento Di Neuroscienze, Psicologia

[9] Lund University,Department of Experimental Medical Science, BMC C12, Faculty of Medicine

[10] Area del Farmaco e Salute del Bambino- NEUROFARBA,Experimental Dementia Research Unit, Department of Experimental Medical Science

[11] Università degli Studi di Firenze,Swedish National Infrastructure for Biological Mass Spectrometry (BioMS)

[12] IRCCS Fondazione Don Carlo Gnocchi,Department of Neurodegenerative Science

[13] Lund University,undefined

[14] BMC B11,undefined

[15] Lund University,undefined

[16] Lund University,undefined

[17] The MiND Program,undefined

[18] Van Andel Institute,undefined

来源：

Acta Neuropathologica Communications | / 11卷

关键词：

Induced pluripotent stem cells; Alzheimer’s disease; Hippocampal spheroids; Intracerebral transplantation; Proteomic analysis; Human post-mortem tissue;

D O I：

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摘要：

引用

共 3 条

[1] Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis
Pomeshchik, Yuriy
Velasquez, Erika
Gil, Jeovanis
Klementieva, Oxana
Gidlof, Ritha
Sydoff, Marie
Bagnoli, Silvia
Nacmias, Benedetta
Sorbi, Sandro
Westergren-Thorsson, Gunilla
Gouras, Gunnar K.
Rezeli, Melinda
Roybon, Laurent
ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2023, 11 (01)
[2] Metabolic signatures of human Alzheimer's disease (AD): 1H NMR analysis of the polar metabolome of post-mortem brain tissue
Graham, Stewart F.
Holscher, Christian
Green, Brian D.
METABOLOMICS, 2014, 10 (04) : 744 - 753
[3] Metabolic signatures of human Alzheimer’s disease (AD): 1H NMR analysis of the polar metabolome of post-mortem brain tissue
Stewart F. Graham
Christian Holscher
Brian D. Green
Metabolomics, 2014, 10 : 744 - 753

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