A case of acute eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression and response to all-trans retinoic acid

被引:0
|
作者
R-Q Yu
W Huang
S-J Chen
S-D Jiang
Z Chen
机构
[1] Shanghai Chang-Zheng Hospital,Division of Hematology, Department of Internal Medicine
[2] Laboratory of Molecular Biology,undefined
[3] Shanghai Institute of Hematology,undefined
来源
Leukemia | 1997年 / 11卷
关键词
leukemia; eosinophilic; PML-RAR alpha; retinoic acid;
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摘要
A typical case of eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression is reported. The patient achieved complete remission after oral administration of all-trans retinoic acid without any exposure to cytotoxic agents. The facts strongly suggest that the genetic event occurred at the level of pluripotent stem cells.
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页码:609 / 611
页数:2
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