Dietary Supplements of Vitamins E and C and β-Carotene Reduce Oxidative Stress in Cats with Renal Insufficiency

被引：0
作者：
S. Yu
I. Paetau-Robinson
机构：
[1] Hill's Science and Technology Center,
来源：
Veterinary Research Communications | 2006年 / 30卷
关键词：
antioxidants; cats; DNA damage; oxidative stress; renal insufficiency;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Oxidative stress may contribute to the progression of chronic renal failure. In this study, cats with spontaneous renal insufficiency were fed a dry cat food supplemented with the antioxidants vitamins E and C, and β-carotene for 4 weeks. When compared with healthy cats, cats with renal insufficiency had a tendency to oxidative stress. The antioxidant supplements significantly reduced DNA damage in cats with renal insufficiency as evidenced by reduced serum 8-OHdG and comet assay parameters. Therefore, supplements of vitamins E and C and β-carotene as antioxidants may be beneficial to cats with renal disease.
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页码：403 / 413
页数：10
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