Pregnancy after treatment of secondary acute promyelocytic leukemia following Hodgkin's disease: a case report

被引:0
作者
I Elezović
M Čolović
D Tomin
D Bošković
机构
[1] Institute of Haematology Clinical Center of Serbia,
来源
Medical Oncology | 2000年 / 17卷
关键词
Hodgkin's disease; chemotherapy; radiotherapy; therapy-related acute promyelocytic leukemia; pregnancy;
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摘要
The authors report a case of therapy-related acute promyelocytic leukemia (t-APL), with typical cytogenetic translocation t(15;17), which appeared following chemotherapy (ABVD), and radiotherapy for Hodgkin's disease (IIB). After treatment with all-trans retinoic acid (Vesanoid® 45 mg/m2 daily) complete remission of t-APL was achieved. Then only one course of chemotherapy ‘3+7’ (doxorubicin 45 mg/m2 1–3 d, cytosar 200 mg/m2 1–7d) was applied and the patient interrupted further treatment in July 1994. Four years later she had a normal pregnancy and delivered a healthy female infant in December 1998.
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页码:222 / 224
页数:2
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