Investigation of the oxidation-reduction transformations of derivatives of dipyrimido[4,5-b][4′,5′-e][1,4]thiazine

被引:0
作者
Nemeryuk M.P. [1 ]
Grigor'ev N.B. [1 ]
Traven' N.I. [1 ]
Levina V.I. [1 ]
Dekhtyarev E.V. [1 ]
Safonova T.S. [1 ]
机构
[1] Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow
关键词
Oxidation; Oxygen; Organic Chemistry; Free Radical; Ascorbic Acid;
D O I
10.1007/BF02290873
中图分类号
学科分类号
摘要
The oxidation-reduction characteristics of both the free radical and the reduced forms of dipyrimido[4,5-b][4′,5′-e][1,4]thiazine derivatives were studied by polarography. It was found that these compounds can participate in oxidation-reduction reactions, such as the oxidation of thiols and ascorbic acid (the radical form) and the reduction of oxygen (the reduced form). This makes it possible to regard them as a system capable of modelling certain oxidation-reduction processes that take place in the living organism. ©1998 Plenum Publishing Corporation.
引用
收藏
页码:1215 / 1218
页数:3
相关论文
共 8 条
[1]  
Ikeuchi Y., Tanaka K., King C., Yoneda F., Chem. Pharm. Bull., 40, (1992)
[2]  
King C., Tanaka K., Yoneda F., Chem. Pharm. Bull., 38, (1990)
[3]  
King C., Tanaka K., Yoneda F., Chem. Pharm. Bull., 38, (1990)
[4]  
Nemeryuk M.P., Traven N.I., Arutyunyan T.G., Shatukhina E.A., Nersesyan N.A., Anisimova O.S., Solov'eva N.P., Peresleni E.M., Sheinker Yu.N., Sokol O.G., Kazakova V.M., Safonova T.S., Khim. Geterotsikl. Khim., 2, (1989)
[5]  
Solov'eva N.P., Anisimova O.S., Sheinker Yu.N., Nemeryuk M.P., Traven N.I., Arutyunyan T.G., Shatukhina E.A., Safonova T.S., Khim. Geterotsikl. Khim., 10, (1992)
[6]  
Timmermans J., Physicochemical Constants of Pure Organic Compounds, (1950)
[7]  
Bruschweiler A., Minkoff G.S., Anal. Chim. Acta, 12, (1955)
[8]  
Fenner H., Granert R.W., Tasendorf L., Arch. Pharm., 314, (1981)