Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment

被引:0
作者
Yanyun Gao
Patrick Dorn
Shengchen Liu
Haibin Deng
Sean R. R. Hall
Ren-Wang Peng
Ralph A. Schmid
Thomas M. Marti
机构
[1] Inselspital,Department of General Thoracic Surgery
[2] Bern University Hospital,Department of BioMedical Research
[3] University of Bern,Department of Intensive Care Medicine
[4] Inselspital,undefined
[5] Bern University Hospital,undefined
来源
Cancer Cell International | / 19卷
关键词
Lung cancer; NSCLC; Chemotherapy; Cisplatin; Pemetrexed; Resistance; Mitochondrial activity; Mitochondrial mass;
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[1]  
Treat J(2012)Comparison of pemetrexed plus cisplatin with other first-line doublets in advanced non-small cell lung cancer (NSCLC): a combined analysis of three phase 3 trials Lung Cancer 76 222-227
[2]  
Scagliotti GV(2011)Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria Proc Natl Acad Sci USA 108 15163-15168
[3]  
Peng G(2012)Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis Cell 148 259-272
[4]  
Monberg MJ(2015)Targeting mitochondria metabolism for cancer therapy Nat Chem Biol 11 9-15
[5]  
Obasaju CK(2015)High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant Oncotarget 6 30472-30486
[6]  
Socinski MA(2015)Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease Oncotarget 6 4569-4584
[7]  
Anderson DD(2014)Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function Nature 514 628-632
[8]  
Quintero CM(2016)Migration and invasion of drug-resistant lung adenocarcinoma cells are dependent on mitochondrial activity Exp Mol Med 48 e277-546
[9]  
Stover PJ(2011)Kinetics of the cell biological changes occurring in the progression of DNA damage-induced senescence Mol Cells 31 539-893
[10]  
Zhang WC(2015)Polyploidy Formation in doxorubicin-treated cancer cells can favor escape From senescence Neoplasia 17 882-574