Ion channels: recent progress and prospects

被引：0
|
作者：
Shin-Ho Chung
Serdar Kuyucak
机构：
[1] Department of Theoretical Physics,
[2] Research School of Physical Sciences,undefined
[3] Australian National University,undefined
[4] Canberra,undefined
[5] ACT 0200,undefined
[6] Australia,undefined
来源：
European Biophysics Journal | 2002年 / 31卷
关键词：
Ion channels Brownian dynamics Molecular dynamics Potassium channels;
D O I：
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中图分类号：
学科分类号：
摘要：
Determination of the crystal structure of the KcsA potassium channel and its subsequent refinement at 2 Å resolution have stimulated much interest in modelling of ion channels. Here we review the recent developments in ion channels research, focusing especially on the question of structure-function relationships, and discuss how permeation models based on Brownian and molecular dynamics simulations can be used fruitfully in this endeavour.
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页码：283 / 293
页数：10
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